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一种位于躯干的罕见软组织肿瘤:骨化性纤维黏液样肿瘤。

A rare soft tissue tumor located in the trunk: Ossifying fibromyxoid tumor.

作者信息

Dere Yelda, Çelik Serkan Yaşar, Çelik Özgür İlhan, Dere Özcan

机构信息

Department of Pathology, Muğla Sıtkı Koçman University School of Medicine, Muğla, Turkey.

Department of General Surgery, Muğla Sıtkı Koçman University School of Medicine, Muğla, Turkey.

出版信息

Turk J Surg. 2015 Jul 14;33(4):299-301. doi: 10.5152/UCD.2015.3087. eCollection 2017.

Abstract

Ossifying fibromyxoid tumor (OFMT), a rare soft tissue tumor, is generally located in the extremities with a distinct morphology characterized by bland, small cells lying in a fibromyxoid stroma and a peripheral rim of the lamellar bone. These tumors mostly express Leu-7, neuron specific enolase in addition to S-100 and vimentin. Some tumors may have malignant cytological features with aggressive behavior but even in classical morphology, recurrence or metastasis can be detected. Thus, the outcome of the tumor remains a mystery and depends on the different results detected during the follow up. Herein, we report a case of OFMT regarding this entity in the differential diagnosis of subcutaneous masses.

摘要

骨化性纤维黏液样肿瘤(OFMT)是一种罕见的软组织肿瘤,通常位于四肢,具有独特的形态,其特征为温和的小细胞位于纤维黏液样基质中,并伴有板层骨的周边边缘。这些肿瘤除了表达S-100和波形蛋白外,大多还表达Leu-7和神经元特异性烯醇化酶。一些肿瘤可能具有恶性细胞学特征且行为侵袭性,但即使是经典形态的肿瘤,也可检测到复发或转移。因此,该肿瘤的预后仍是个谜,取决于随访期间检测到的不同结果。在此,我们报告一例OFMT病例,该病例涉及皮下肿块鉴别诊断中的这一实体。

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