Drakhshandeh Dori, Miller James A, Fabiano Andrew J
Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, New York, USA.
Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, New York, USA; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.
World Neurosurg. 2018 Mar;111:e403-e409. doi: 10.1016/j.wneu.2017.12.081. Epub 2017 Dec 21.
Spinal stabilization surgery is an integral part of the treatment of spinal metastatic disease. Bony fusion is the hallmark of spinal stabilization in non-oncology patients. Spinal oncology patients are unlikely to achieve bony fusion because of their overall prognosis and concurrent therapies. Stabilization surgery without fusion may be a reasonable approach for these patients. Literature evaluating the effectiveness of this approach is limited. The object of this study was to investigate the rate of instrumentation failure in patients undergoing posterior spinal instrumented stabilization without fusion for spinal metastatic disease.
Data from consecutive cases of spinal surgery at our institution during an 81-month period were reviewed. Demographics, clinical notes, and computed tomography findings were recorded and used to evaluate instrumentation failures. Patients who underwent separation surgery that included laminectomy and posterior spinal instrumentation without fusion for spinal metastatic disease and had follow-up computed tomography scans >3 months postoperatively were selected for the study.
Twenty-seven patients were included in the study. Mean age was 64.85 ± 6.53 years. Nine patients were women. A mean of 1.61 ± 0.96 laminectomy levels was performed. A mean of 8.26 ± 1.48 screws was inserted. The mean postoperative discharge date was 5.07 ± 1.47 days. Mean follow-up duration was 12.17 ± 11.73 months. None of the patients had a change in instrumentation position, pedicle screw pullout, change in spinal alignment, or progressive deformity. No patient required reoperation or instrumentation revision or replacement.
Our experience suggests that instrumented spinal stabilization without fusion is an acceptable approach for patients with spinal metastatic disease.
脊柱稳定手术是脊柱转移性疾病治疗的重要组成部分。骨融合是非肿瘤患者脊柱稳定的标志。脊柱肿瘤患者由于其总体预后和并发治疗,不太可能实现骨融合。对于这些患者,不进行融合的稳定手术可能是一种合理的方法。评估这种方法有效性的文献有限。本研究的目的是调查因脊柱转移性疾病接受后路脊柱内固定稳定手术但不进行融合的患者的内固定失败率。
回顾了我们机构在81个月期间连续脊柱手术病例的数据。记录人口统计学、临床记录和计算机断层扫描结果,并用于评估内固定失败情况。选择接受包括椎板切除术和后路脊柱内固定但不进行融合的脊柱转移性疾病分离手术且术后随访计算机断层扫描超过3个月的患者进行研究。
27例患者纳入研究。平均年龄为64.85±6.53岁。9例为女性。平均进行1.61±0.96个椎板切除节段。平均植入8.26±1.48枚螺钉。术后平均出院日期为5.07±1.47天。平均随访时间为12.17±11.73个月。所有患者均未出现内固定位置改变、椎弓根螺钉拔出、脊柱排列改变或进行性畸形。没有患者需要再次手术或内固定翻修或更换。
我们的经验表明,对于脊柱转移性疾病患者,不进行融合的脊柱内固定稳定手术是一种可接受的方法。