Hwang Mikayla E
Radiol Technol. 2018 Jan;89(3):224-237.
A systematic literature review was performed to evaluate the effectiveness of abdominal sonography and abdominal computed tomography (CT) in diagnosing acute appendicitis in adult and pediatric patients.
Peer-reviewed literature published between 1986 and 2014 was searched using multiple medical literature databases. Studies included in this review were conducted on human patients; included more than 50 patients; reported diagnostic values; evaluated pediatric patients, adults, or both (pregnant women excluded); and used histological results from surgery or clinical follow-up as a reference standard.
In the sonography studies, the calculated pooled values of sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 86%, 94%, 100%, and 92%, respectively. In the CT studies, the calculated pooled values of sensitivity, specificity, PPV, and NPV were 95%, 94%, 95%, and 99%, respectively.
Unenhanced CT is used frequently to minimize harmful effects of radiation, especially for pediatric patients. Performing sonography can reduce the cost of a negative exploration, which can generate unnecessary financial burdens for patients.
This study suggests that sonography is an effective first-line diagnostic tool for acute appendicitis and that CT should be performed for patients with inconclusive sonographic findings.
进行一项系统的文献综述,以评估腹部超声和腹部计算机断层扫描(CT)在诊断成人和儿童急性阑尾炎中的有效性。
使用多个医学文献数据库检索1986年至2014年间发表的同行评审文献。本综述纳入的研究针对人类患者开展;纳入患者超过50例;报告了诊断价值;评估了儿科患者、成人或两者(排除孕妇);并将手术组织学结果或临床随访作为参考标准。
在超声检查研究中,计算得出的敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV)的合并值分别为86%、94%、100%和92%。在CT研究中,计算得出的敏感性、特异性、PPV和NPV的合并值分别为95%、94%、95%和99%
未增强CT经常被用于将辐射的有害影响降至最低,尤其是对儿科患者。进行超声检查可以降低阴性探查的成本,阴性探查会给患者带来不必要的经济负担。
本研究表明,超声检查是急性阑尾炎有效的一线诊断工具,对于超声检查结果不明确的患者应进行CT检查。