前列腺素E2和前列腺素D2-甲基肟甲酯及其类似物的顺式和反式异构体的质谱裂解模式。
Mass spectrometric fragmentation patterns for the syn and anti isomers of PGE2 and PGD2-methyloxime methyl esters and their analogs.
作者信息
Hartzell C J, Andersen N H
出版信息
Biomed Mass Spectrom. 1985 Jul;12(7):303-8. doi: 10.1002/bms.1200120702.
PMID:2933087
Abstract
A systematic study of the mass spectral fragmentation of the methyl ester-methyloxime-trimethylsilyl ether derivatives of D and E prostaglandins and selected omega-chain analogs is presented. Fragments from the omega-chain analogs are shifted the appropriate mass when compared with the parent PGD2 or PGE2. NMR data of the methyloxime methyl ester of PGE2 have permitted assignment of the syn and anti isomers (relative to the alpha chain) to the fast and slow eluting gas chromatographic peaks, respectively.
摘要
本文介绍了对D和E前列腺素及其选定的ω链类似物的甲酯-甲基肟-三甲基硅醚衍生物的质谱碎裂情况进行的系统研究。与母体PGD2或PGE2相比，ω链类似物的碎片质量发生了相应的偏移。PGE2的甲基肟甲酯的核磁共振数据已使顺式和反式异构体（相对于α链）分别对应于快速和慢速洗脱的气相色谱峰。
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