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用于运动障碍的立体定向射频毁损术

Stereotactic Radiofrequency Lesioning for Movement Disorders.

作者信息

Taira Takaomi, Horisawa Shiro, Takeda Nobuhiko, Ghate Prajakta

出版信息

Prog Neurol Surg. 2018;33:107-119. doi: 10.1159/000481079. Epub 2018 Jan 12.

Abstract

During the past 2 decades, deep brain stimulation (DBS) took over the position of radiofrequency (RF) lesioning of thalamic or pallidal targets for control of movement disorders. Superiority of DBS over RF lesioning is widely accepted, and most neurosurgeons even regard RF lesioning to be old-fashioned and dangerous. Such concepts emerged from the data of old stereotactic operations with ventriculography and without computerized planning. Hardware-related complications are not negligible in long-term DBS therapy, and DBS only controls the symptoms. Living with an implanted device is also a burden for patients. With modern stereotactic techniques, RF lesioning is safe and effective. Indication of RF lesioning includes various types of tremor, focal hand dystonia, and even generalized or segmental dystonias. Neurosurgeons armed with both the procedures can choose the best treatment modality for patients.

摘要

在过去的20年里,深部脑刺激(DBS)取代了丘脑或苍白球靶点的射频(RF)毁损术,用于控制运动障碍。DBS相对于RF毁损术的优越性已被广泛接受,大多数神经外科医生甚至认为RF毁损术过时且危险。这些观念源于旧的立体定向手术数据,这些手术采用脑室造影且无计算机辅助规划。在长期的DBS治疗中,与硬件相关的并发症不容忽视,而且DBS仅能控制症状。植入设备对患者来说也是一种负担。随着现代立体定向技术的发展,RF毁损术是安全有效的。RF毁损术的适应症包括各种类型的震颤、局限性手部肌张力障碍,甚至全身性或节段性肌张力障碍。掌握这两种手术方法的神经外科医生可以为患者选择最佳的治疗方式。

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