一种针对 HIV 感染者慢性疼痛的新型行为干预的随机先导试验。
A Randomized Pilot Trial of a Novel Behavioral Intervention for Chronic Pain Tailored to Individuals with HIV.
机构信息
Divisions of General Internal Medicine and Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, 230 McKee Place Suite 600, Pittsburgh, PA, 15213, USA.
Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
出版信息
AIDS Behav. 2018 Aug;22(8):2733-2742. doi: 10.1007/s10461-018-2028-2.
Chronic pain is an important and understudied comorbidity in people living with HIV (PLWH). We conducted a pilot trial of Skills TO Manage Pain (STOMP), an innovative social cognitive theory-based pain self-management intervention tailored to PLWH, to assess feasibility, acceptability, and preliminary efficacy. Eligibility criteria included being HIV+, ≥ moderate pain for ≥ 3 months and a score of ≥ 4 on the three-item PEG pain severity and interference scale. Participants were randomized in a 1:1 fashion to STOMP or a usual care comparison. Among 22 participants randomized to STOMP, median session attendance was 9/12 (75%). Of 19 STOMP participants surveyed, 13 reported being "much better" overall since beginning treatment. Brief pain inventory-total scores decreased by 2 points in the intervention group and 0.9 in the control group (p = 0.11). STOMP is feasible, acceptable, and shows preliminary evidence of efficacy and promise for a full-scale trial.
慢性疼痛是艾滋病毒感染者（PLWH）中一个重要但研究不足的共病。我们开展了一项 Skills TO Manage Pain（STOMP）的试点试验，这是一种针对 PLWH 的创新基于社会认知理论的疼痛自我管理干预措施，旨在评估其可行性、可接受性和初步疗效。入选标准包括 HIV+，≥3 个月的中度疼痛和三个项目 PEG 疼痛严重程度和干扰量表的评分≥4。参与者以 1:1 的比例随机分配到 STOMP 或常规护理对照组。在随机分配到 STOMP 的 22 名参与者中，中位数出席 9/12（75%）次。在接受调查的 19 名 STOMP 参与者中，有 13 人报告自开始治疗以来总体上“好得多”。干预组的简明疼痛量表总分下降 2 分，对照组下降 0.9 分（p=0.11）。STOMP 是可行的、可接受的，并且初步证明了其疗效和在全规模试验中的前景。
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