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贝伐单抗眼内注射治疗脉络膜新生血管性黄斑水肿

Suture Stenting of a Tube Fenestration for Early Intraocular Pressure Control After Baerveldt Glaucoma Implant Surgery.

机构信息

New York Eye and Ear Infirmary of Mount Sinai, New York, NY.

出版信息

J Glaucoma. 2018 Mar;27(3):291-296. doi: 10.1097/IJG.0000000000000885.

Abstract

PURPOSE

To evaluate the efficacy and safety of a tube fenestration stented with a 10-0 polyglactin suture for controlling early postoperative intraocular pressure (IOP) after Baerveldt glaucoma implant (BGI) surgery.

METHODS

The medical records of 110 patients (119 eyes) who underwent BGI surgery with a tube fenestration stented with a 10-0 polyglactin suture anterior to an occlusive tube ligature were retrospectively reviewed. Main outcome measures included IOP and number of glaucoma medications at postoperative day 1, week 1, and weeks 2 to 3 as well as complications occurring before ligature release.

RESULTS

Mean±SD preoperative IOP was 30.9±9.3 mm Hg using an average of 3.8±1.1 glaucoma medications. A statistically significant reduction in IOP and glaucoma medications was observed at all timepoints during the first 3 postoperative weeks compared with baseline (P<0.001). Mean IOP on postoperative day 1, week 1, and weeks 2 to 3 was 18.4±12.2 mm Hg on no medication, 15.9±9.4 mm Hg on 1.0±1.3 medications, and 16.7±8.2 mm Hg on 1.2±1.5 medications, respectively. In total, 44 eyes (37%) achieved IOP control without glaucoma medication during period of tube occlusion.

CONCLUSIONS

The use of a single, monofilament 10-0 polyglactin suture to stent a fenestration proximal to the occlusive ligature of a BGI tube is effective in controlling IOP in the early postoperative period. Hypotony-related complications were infrequent and resolved in all cases with in-office interventions.

摘要

目的

评估在 Baerveldt 青光眼植入物(BGI)手术后,使用 10-0 聚甘醇酸缝线对引流管造口进行管窗缝合以控制术后早期眼内压(IOP)的疗效和安全性。

方法

回顾性分析了 110 例(119 只眼)接受 BGI 手术并在前部闭塞管结扎处用 10-0 聚甘醇酸缝线进行管窗缝合的患者的病历。主要观察指标包括术后第 1、1 周和第 2-3 周的 IOP 和降眼压药物的使用次数,以及结扎释放前发生的并发症。

结果

平均(±SD)术前 IOP 为 30.9±9.3mmHg,平均使用 3.8±1.1 种降眼压药物。与基线相比,术后第 1、1 周和第 2-3 周的所有时间点的 IOP 和降眼压药物均显著降低(P<0.001)。术后第 1、1 周和第 2-3 周的平均 IOP 分别为无药物时的 18.4±12.2mmHg、有 1.0±1.3 种药物时的 15.9±9.4mmHg、有 1.2±1.5 种药物时的 16.7±8.2mmHg。总共有 44 只眼(37%)在管阻塞期间无需降眼压药物即可控制 IOP。

结论

在 BGI 管的闭塞结扎物近端使用单根、单丝 10-0 聚甘醇酸缝线进行管窗缝合,可有效控制术后早期的 IOP。与低眼压相关的并发症发生率较低,所有病例均通过门诊干预得到解决。

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