Mica Michael Conti, Voronov Leonard I, Carandang Gerard, Havey Robert M, Wojewnik Bartosz, Patwardhan Avinash G
Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center, Maywood, Illinois.
Musculoskeletal Biomechanics Laboratory, Department of Veterans Affairs, Edward Hines Jr. VA Hospital, Hines, Illinois.
Int J Spine Surg. 2017 Aug 1;11(4):24. doi: 10.14444/4024. eCollection 2017.
A novel expandable lumbar interbody fusion cage has been developed which allows for a broad endplate footprint similar to an anterior lumbar interbody fusion (ALIF); however, it is deployed from a minimally invasive transforaminal unilateral approach. The perceived benefit is a stable circumferential fusion from a single approach that maintains the anterior tension band of the anterior longitudinal ligament.The purpose of this biomechanics laboratory study was to evaluate the biomechanical stability of an expandable lumbar interbody cage inserted using a transforaminal approach and deployed in situ compared to a traditional lumbar interbody cage inserted using an anterior approach (control device).
Twelve cadaveric spine specimens (L1-L5) were tested intact and after implantation of both the control and experimental devices in two (L2-L3 and L3-L4) segments of each specimen; the assignments of the control and experimental devices to these segments were alternated. Effect of supplemental pedicle screw-rod stabilization was also assessed. Moments were applied to the specimens in flexion-extension (FE), lateral bending (LB), and axial rotation (AR). The effect of physiologic preload on construct stability was evaluated in FE. Segmental motions were measured using an optoelectronic motion measurement system.
The deployable expendable TLIF cage and control devices significantly reduced FE motion with and without compressive preload when compared to the intact condition (p<0.05). Segmental motions in LB and AR were also significantly reduced with both devices (p<0.05). Under no preload, the deployable expendable TLIF cage construct resulted in significantly smaller FE motion compared to the control cage construct (p<0.01). Under all other testing modes (FE under 400N preload, LB, and AR) the postoperative motions of the two constructs did not differ statistically (p>0.05). Adding bilateral pedicle screws resulted in further reduction of ROM for all loading modes compared to intact condition, with no statistical difference between the two constructs (p>0.05).
The ability of the deployable expendable interbody cage in reducing segmental motions was equivalent to the control cage when used as a stand-alone construct and also when supplemented with bilateral pedicle screw-rod instrumentation. The larger footprint of the fully deployed TLIF cage combined with preservation of the anterior soft-tissue tension band may provide a better biomechanical fusion environment by combining the advantages of the traditional ALIF and TLIF approaches.
已研发出一种新型可扩张腰椎椎间融合器,其终板覆盖面积大,类似于前路腰椎椎间融合术(ALIF);然而,它是通过微创经椎间孔单侧入路置入的。其预期优势是通过单一入路实现稳定的环形融合,同时保留前纵韧带的前张力带。本生物力学实验室研究的目的是评估经椎间孔入路置入并原位展开的可扩张腰椎椎间融合器与采用前路入路置入的传统腰椎椎间融合器(对照装置)相比的生物力学稳定性。
对12个尸体脊柱标本(L1 - L5)进行完整测试,并在每个标本的两个节段(L2 - L3和L3 - L4)分别植入对照装置和实验装置;对照装置和实验装置在这些节段的分配是交替的。还评估了附加椎弓根螺钉 - 棒固定的效果。对标本施加屈伸(FE)、侧弯(LB)和轴向旋转(AR)力矩。在FE中评估生理预负荷对固定结构稳定性的影响。使用光电运动测量系统测量节段运动。
与完整状态相比,可展开的可扩张经椎间孔腰椎椎间融合器(TLIF)笼和对照装置在有和无压缩预负荷时均显著降低了FE运动(p<0.05)。两种装置在LB和AR中的节段运动也显著降低(p<0.05)。在无预负荷情况下,与对照笼结构相比,可展开的可扩张TLIF笼结构导致的FE运动显著更小(p<0.01)。在所有其他测试模式下(400N预负荷下的FE、LB和AR),两种结构的术后运动无统计学差异(p>0.05)。与完整状态相比,添加双侧椎弓根螺钉导致所有加载模式下的活动度进一步降低,两种结构之间无统计学差异(p>0.05)。
可展开的可扩张椎间融合器作为单独结构使用时,以及在补充双侧椎弓根螺钉 - 棒器械时,减少节段运动的能力与对照笼相当。完全展开的TLIF笼更大的覆盖面积与保留前软组织张力带相结合,可能通过结合传统ALIF和TLIF方法的优势提供更好的生物力学融合环境。