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癫痫患儿与健康儿童口腔卫生状况及牙龈增生的比较评估:与各种抗癫痫药物的关系

Comparative evaluation of oral hygiene status and gingival enlargement among epileptic and healthy children as related to various antiepileptic drugs.

作者信息

Joshi Neelam Hasmukhbhai, Deshpande Anshula Neeraj, Deshpande Neeraj Chandrahas, Rathore Ashutosh Singh

机构信息

Department of Paedodontics and Preventive Dentistry, K. M. Shah Dental College and Hospital, Vadodara, Gujarat, India.

Department of Periodontics and Oral Implantology, K. M. Shah Dental College and Hospital, Vadodara, Gujarat, India.

出版信息

J Indian Soc Periodontol. 2017 Mar-Apr;21(2):125-129. doi: 10.4103/jisp.jisp_48_17.

Abstract

BACKGROUND

Epilepsy is a gathering of neurological disorders characterized by epileptic seizures. Epileptic children, who are on active treatment with antiepileptic drugs, have a well-recognized side effect of gingival enlargement. Therefore, all efforts should be made, particularly for the population who are diagnosed or affected by the systemic disease. This study was conducted with an aim to determine oral hygiene status and gingival enlargement among epileptic and healthy children as related to various antiepileptic drugs.

MATERIALS AND METHODS

The cross-sectional observational study was conducted in the department of pedodontics and attached general hospital. A sample size of 120 participants with 60 healthy and 60 epileptic children between age 2 and 14 years were included. Oral health status of participants was examined using oral hygiene simplified index and plaque index. Gingival enlargement was assessed using Miranda-Brunet index. For statistical analysis, one-way ANOVA test, independent -test, and Pearson's Chi-square test were used.

RESULTS

From the total participants included in the study, 49% of participants had good oral hygiene from healthy group, and 28% participants had poor oral hygiene from the epileptic group. Sodium valproate was the most common drug used and was associated with increased gingival enlargement.

CONCLUSION

Conclusion can be drawn that epileptic children under medication had poor oral hygiene and an increased risk for gingival enlargement as compared to their healthy counterparts. It must be stressed that the epileptic patients should be given dental care without conditions and provided with best possible care to restore esthetics and functions.

摘要

背景

癫痫是一组以癫痫发作特征的神经系统疾病。正在接受抗癫痫药物积极治疗的癫痫儿童存在公认的牙龈增生副作用。因此,应尽一切努力,特别是针对被诊断患有全身性疾病或受其影响的人群。本研究旨在确定癫痫儿童和健康儿童的口腔卫生状况以及与各种抗癫痫药物相关的牙龈增生情况。

材料与方法

在儿童牙科及附属综合医院进行横断面观察性研究。纳入120名参与者,其中60名健康儿童和60名2至14岁的癫痫儿童。使用简化口腔卫生指数和菌斑指数检查参与者的口腔健康状况。使用米兰达 - 布鲁内特指数评估牙龈增生情况。进行统计分析时,使用单向方差分析测试、独立样本t检验和皮尔逊卡方检验。

结果

在纳入研究的所有参与者中,健康组49%的参与者口腔卫生良好,癫痫组28%的参与者口腔卫生较差。丙戊酸钠是最常用的药物,且与牙龈增生增加有关。

结论

可以得出结论,与健康儿童相比,正在服药的癫痫儿童口腔卫生较差,牙龈增生风险增加。必须强调的是,应无条件地为癫痫患者提供牙科护理,并给予尽可能好的护理以恢复美观和功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d36/5771109/1c5005d535e6/JISP-21-125-g002.jpg

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