From the Department of Nuclear Medicine & PET Center, Aarhus University Hospital, Aarhus, Denmark.
Clin Nucl Med. 2018 Apr;43(4):267-268. doi: 10.1097/RLU.0000000000001988.
We describe a case of a 73-year-old man with newly diagnosed prostate cancer referred to Ga-PSMA PET/CT for staging. A focal uptake of PSMA was visualized in the prostate compatible with primary prostate cancer. Outside the prostate, a PSMA-avid paravertebral soft tissue mass was observed. Further investigation with MRI of the same region showed signs compatible with schwannoma. This case shows the importance of including schwannoma in the differential diagnostic evaluation of patients with Ga-PSMA-positive foci in paravertebral locations, as schwannomas may show avid PSMA uptake and may potentially lead to an incorrect diagnosis of metastasis.
我们描述了一例 73 岁男性新诊断为前列腺癌,行 Ga-PSMA PET/CT 分期。在前列腺内可见与原发性前列腺癌一致的 PSMA 摄取焦点。在前列腺外,观察到 PSMA 摄取的椎旁软组织肿块。同一区域的 MRI 进一步检查显示符合神经鞘瘤的征象。该病例表明,在 Ga-PSMA 阳性椎旁病灶的鉴别诊断评估中,包括神经鞘瘤的重要性,因为神经鞘瘤可能显示 PSMA 摄取活跃,并可能导致转移的错误诊断。