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评估在牙槽嵴保存中使用富血小板纤维蛋白并联合或不联合骨替代物的牙槽窝填塞技术的疗效:一项前瞻性随机对照研究。

To assess the efficacy of socket plug technique using platelet rich fibrin with or without the use of bone substitute in alveolar ridge preservation: a prospective randomised controlled study.

作者信息

Girish Kumar N, Chaudhary Rupanzal, Kumar Ish, Arora Srimathy S, Kumar Nilesh, Singh Hem

机构信息

Department of Oral and Maxillofacial Surgery, Swami Devi Dyal Hospital & Dental College, Barwala, Panchkula, India.

出版信息

Oral Maxillofac Surg. 2018 Jun;22(2):135-142. doi: 10.1007/s10006-018-0680-3. Epub 2018 Feb 6.

Abstract

AIM

The purpose of this study is to evaluate the efficacy of Platelet Rich Fibrin (PRF) as a socket plug with or without use of Plaster of Paris (POP) as bone substitute to preserve the alveolar ridge post-extraction.

MATERIAL AND METHODS

A prospective randomised single blind controlled study, was conducted for 18 months from November 2014 to May 2016 on 48 patients requiring extraction. All teeth were extracted atraumatically using periotomes and luxators without raising mucoperiosteal flap. Sockets were randomly allotted to groups A, B and C. Group A sockets were chosen as control, where figure of eight suture was placed. In group B sockets, PRF obtained by centrifugation was used as a socket plug and stabilised with figure of eight suture. Group C sockets were filled with POP and then covered with PRF. The socket was then closed with a figure of eight suture. Patients were informed of need for 6 months follow-up.

RESULTS

Ninety sockets in 48 patients were subjected to our study. We found that results in the sockets where we have grafted POP showed better ridge preservation and post-operative comfort even though the difference in ridge resorption between the three groups was not statistically significant. Powered by Editorial Manager® and ProduXion Manager® from the Aries Systems Corporation.

CONCLUSION

Atraumatic extraction may minimise the post-operative pain and discomfort to patient as well as the post-extraction alveolar height and width changes. The use of PRF and/or bone substitute even though clinically contributes to better post-operative healing and minimal loss of alveolar width and height, the values were not statistically significant.

摘要

目的

本研究旨在评估富血小板纤维蛋白(PRF)作为牙槽窝填充物,在使用或不使用巴黎石膏(POP)作为骨替代物的情况下,对拔牙后牙槽嵴保存的疗效。

材料与方法

2014年11月至2016年5月,对48例需要拔牙的患者进行了一项为期18个月的前瞻性随机单盲对照研究。所有牙齿均使用牙挺和骨膜分离器进行无创拔除,不掀起粘骨膜瓣。牙槽窝随机分为A、B、C三组。A组牙槽窝作为对照组,采用8字缝合。B组牙槽窝使用通过离心获得的PRF作为牙槽窝填充物,并用8字缝合固定。C组牙槽窝先填充POP,然后覆盖PRF。然后用8字缝合关闭牙槽窝。告知患者需要进行6个月的随访。

结果

48例患者的90个牙槽窝纳入本研究。我们发现,植入POP的牙槽窝在牙槽嵴保存和术后舒适度方面表现更好,尽管三组之间牙槽嵴吸收的差异无统计学意义。由Aries Systems Corporation的Editorial Manager®和ProduXion Manager®提供支持。

结论

无创拔牙可将患者术后疼痛和不适以及拔牙后牙槽嵴高度和宽度的变化降至最低。使用PRF和/或骨替代物尽管在临床上有助于更好的术后愈合以及最小化牙槽嵴宽度和高度的丧失,但这些数值无统计学意义。

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