Clyburn P, Kay N H, McKenzie P J
Br J Anaesth. 1986 Aug;58(8):872-5. doi: 10.1093/bja/58.8.872.
Sixty patients were randomly allocated in an open study to receive either midazolam or diazepam (Diazemuls) with fentanyl and etomidate for induction and maintenance of anaesthesia during day-stay gynaecological surgery. The excitatory effects of etomidate were controlled by the benzodiazepine-fentanyl combination in both groups. No significant difference in the quality of recovery (as judged by Trieger test analysis), amnesia, incidence of recall of pain on injection of etomidate or nausea and vomiting could be demonstrated between the groups. There was a high degree (97%) of patient acceptance.
在一项开放性研究中,60名患者被随机分配,在日间妇科手术中接受咪达唑仑或地西泮(安定乳剂)与芬太尼和依托咪酯联合使用,用于诱导和维持麻醉。两组中依托咪酯的兴奋作用均通过苯二氮䓬类-芬太尼联合用药得到控制。两组之间在恢复质量(通过Trieger试验分析判断)、遗忘、注射依托咪酯时疼痛回忆的发生率或恶心呕吐方面均未显示出显著差异。患者接受度很高(97%)。