中枢性睡眠增多症的临床进展
Clinical update on central hypersomnias.
作者信息
Pérez-Carbonell Laura, Leschziner Guy
机构信息
Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital, London, UK.
Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
出版信息
J Thorac Dis. 2018 Jan;10(Suppl 1):S112-S123. doi: 10.21037/jtd.2017.10.161.
Abstract
The central hypersomnias encompass a range of conditions causing persisting or intermittent excessive daytime sleepiness (EDS). These conditions therefore present not infrequently in general clinical sleep practice, and remain in the differential for patients presenting with sleepiness. Our understanding of the pathophysiology, diagnosis and management of these conditions has progressed significantly over recent years, and in this article we review this group of disorders, focussing in particular on recent changes in classification and diagnosis, pathophysiological advances, and novel treatment options.
摘要
中枢性睡眠增多症包括一系列导致持续性或间歇性日间过度嗜睡（EDS）的病症。因此，这些病症在一般临床睡眠实践中并不少见，并且在出现嗜睡症状的患者鉴别诊断中仍然存在。近年来，我们对这些病症的病理生理学、诊断和管理的认识有了显著进展，在本文中，我们将对这组疾病进行综述，特别关注分类和诊断的最新变化、病理生理学进展以及新的治疗选择。
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