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使用氰基丙烯酸酯胶水进行前上固定鼓膜成形术可避免在中耳腔内填塞明胶海绵。

Anterosuperior anchoring myringoplasty using cyanoacrylate glue can prevent packing gelfoam in the middle ear cavity.

作者信息

Li Y, Liang J, Cheng Y, Zhang Q, Ren X, Sheng Y

机构信息

Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China.

Department of Digestive Diseases, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Apr;135(2):95-98. doi: 10.1016/j.anorl.2017.04.002. Epub 2018 Feb 12.

Abstract

OBJECTIVES

Although a number of methods have been attempted to improve securing the graft, packing gelfoam in the middle ear cavity cannot be avoided, which could obstruct the tympanic ostium of the Eustachian tube and affect inner ear function. Myringoplasty using tissue adhesive has gained traction because tissue adhesives can effectively stabilise the graft and act as scaffolding to improve the graft uptake. The aim of this prospective study was to explore myringoplasty using cyanoacrylate glue with no packing in the middle ear cavity for the repair of subtotal tympanic membrane (TM) perforations.

METHODS

Between March 2014 and November 2015, 71 patients with subtotal TM perforations were randomly and prospectively divided into a glue group and a control group. Two securing techniques were performed using only cyanoacrylate glue or using only filling gelfoam in the middle ear cavity, respectively, during an anterosuperior anchoring myringoplasty operated by a single surgeon.

RESULTS

At a 6-month follow-up, the graft uptake rate was 87% in the glue group and 89% in the control group. A significant hearing improvement was found in both groups postoperatively when compared to the preoperative values (P<0.05 for both). There was no significant difference in the graft uptake rate and hearing improvement between the 2 groups (P>0.05). Similar complications were found in each group.

CONCLUSION

Cyanoacrylate glue is a helpful material for graft stabilisation and can substitute for filling gelfoam in the middle ear cavity during anterosuperior anchoring myringoplasty for subtotal TM perforation.

摘要

目的

尽管已经尝试了多种方法来改善移植物的固定,但中耳腔内填充明胶海绵是无法避免的,这可能会阻塞咽鼓管的鼓膜口并影响内耳功能。使用组织粘合剂进行鼓膜成形术越来越受到关注,因为组织粘合剂可以有效地稳定移植物并作为支架来促进移植物的吸收。这项前瞻性研究的目的是探索在中耳腔内不进行填充的情况下,使用氰基丙烯酸酯胶水进行鼓膜成形术来修复鼓膜(TM)次全穿孔。

方法

在2014年3月至2015年11月期间,71例TM次全穿孔患者被随机前瞻性地分为胶水组和对照组。在由同一位外科医生进行的前上固定鼓膜成形术中,分别仅使用氰基丙烯酸酯胶水或仅在中耳腔内填充明胶海绵进行两种固定技术。

结果

在6个月的随访中,胶水组的移植物吸收率为87%,对照组为89%。与术前值相比,两组术后听力均有显著改善(两组均P<0.05)。两组之间的移植物吸收率和听力改善无显著差异(P>0.05)。每组中发现的并发症相似。

结论

氰基丙烯酸酯胶水是一种有助于稳定移植物的材料,在TM次全穿孔的前上固定鼓膜成形术中可替代中耳腔内填充的明胶海绵。

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