Temblador-Barba I, Delgado-Alonso E M, Toribio-García M, Martínez-Campillo L, Molina-Leyva I, Martínez-Jiménez M
Servicio de Oftalmología, Hospital Universitario Virgen de las Nieves, Complejo Hospitalario Universitario, Granada, España.
Servicio de Oftalmología, Hospital Universitario Virgen de las Nieves, Complejo Hospitalario Universitario, Granada, España.
Arch Soc Esp Oftalmol (Engl Ed). 2018 Jul;93(7):350-353. doi: 10.1016/j.oftal.2018.01.005. Epub 2018 Feb 16.
Here we report a 19-year-old female patient who presented a vasoproliferative tumour. It caused complications, such as epiretinal membrane, macular oedema, vitreous haemorrhage, and exudative retinal detachment. The patient was treated with 3 injections of intravitreal bevacizumab, an intravitreal dexamethasone implant, tocilizumab, and double freeze-thaw cryotherapy.
Therapeutic options are: observation, if it is small, if it is a peripheral lesion, and if there seems to be no threat to vision. If it requires treatment, laser photocoagulation, intravitreal bevacizumab, trans-conjunctival cryotherapy, transpupillary thermotherapy, photodynamic therapy, brachytherapy plaques and surgery are the different options available. Recently, tocilizumab and intravitreal dexamethasone implants have been reported to be beneficial.
我们在此报告一名19岁女性患者,其患有血管增生性肿瘤。该肿瘤引发了诸如视网膜前膜、黄斑水肿、玻璃体积血和渗出性视网膜脱离等并发症。患者接受了3次玻璃体内注射贝伐单抗、一次玻璃体内地塞米松植入、托珠单抗治疗以及双重冻融冷冻疗法。
治疗选择包括:若肿瘤较小、为周边病变且似乎对视力无威胁,则进行观察。若需要治疗,激光光凝、玻璃体内注射贝伐单抗、经结膜冷冻疗法、经瞳孔温热疗法、光动力疗法、近距离放射治疗斑块和手术是可供选择的不同方法。最近,有报道称托珠单抗和玻璃体内地塞米松植入有益。