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梅达沃的“主动获得的耐受性”和危险模型:拨乱反正。

Medawar's "actively acquired tolerance" and the Danger model: Setting the record straight.

机构信息

Department of Microbiology and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.

出版信息

Scand J Immunol. 2018 Sep;88(3):e12652. doi: 10.1111/sji.12652. Epub 2018 Mar 25.

Abstract

I describe here what I believe is a misrepresentation of the classic observations of Billingham, Brent and Medawar on "actively acquired tolerance," by Ridge, Fuchs and Matzinger; I set the record straight by revisiting the original literature and discussing the implications of this misinterpretation.

摘要

我在这里描述的是我认为对 Billingham、Brent 和 Medawar 关于“主动获得的耐受”的经典观察结果的一种错误表述,这种错误表述来自 Ridge、Fuchs 和 Matzinger;我通过重新审视原始文献并讨论这种误解的含义来纠正这一错误。

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