Prevalence and clinical challenges among adults with primary immunodeficiency and recombination-activating gene deficiency.
作者信息
Lawless Dylan, Geier Christoph B, Farmer Jocelyn R, Lango Allen Hana, Thwaites Daniel, Atschekzei Faranaz, Brown Matthew, Buchbinder David, Burns Siobhan O, Butte Manish J, Csomos Krisztian, Deevi Sri V V, Egner William, Ehl Stephan, Eibl Martha M, Fadugba Olajumoke, Foldvari Zsofia, Green Deanna M, Henrickson Sarah E, Holland Steven M, John Tami, Klemann Christian, Kuijpers Taco W, Moreira Fernando, Piller Alexander, Rayner-Matthews Paula, Romberg Neil D, Sargur Ravishankar, Schmidt Reinhold E, Schröder Claudia, Schuetz Catharina, Sharapova Svetlana O, Smith Ken G C, Sogkas Georgios, Speckmann Carsten, Stirrups Kathleen, Thrasher Adrian J, Wolf Hermann M, Notarangelo Luigi D, Anwar Rashida, Boyes Joan, Ujhazi Boglarka, Thaventhiran James, Walter Jolan E, Savic Sinisa
机构信息
Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, St James's University Hospital, Leeds, United Kingdom.
Immunology Outpatient Clinic, Vienna, Austria.
出版信息
J Allergy Clin Immunol. 2018 Jun;141(6):2303-2306. doi: 10.1016/j.jaci.2018.02.007. Epub 2018 Mar 2.
Abstract
摘要
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本文引用的文献
1
Abnormalities of T-cell receptor repertoire in CD4 regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity.RAG基因突变患者CD4调节性T细胞和传统T细胞中T细胞受体库的异常：对自身免疫的影响。
J Allergy Clin Immunol. 2017 Dec;140(6):1739-1743.e7. doi: 10.1016/j.jaci.2017.08.001. Epub 2017 Aug 31.
2
Characterization of T and B cell repertoire diversity in patients with RAG deficiency.RAG缺陷患者T和B细胞受体库多样性的特征分析
Sci Immunol. 2016 Dec 16;1(6). doi: 10.1126/sciimmunol.aah6109.
3
Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56 NKG2A Cells, and Yet Display Increased Degranulation and Higher Perforin Content.患有重组激活基因和非同源末端连接基因缺陷患者的自然杀伤细胞中，CD56 NKG2A细胞的频率更高，但脱颗粒增加且穿孔素含量更高。
Front Immunol. 2017 Jul 17;8:798. doi: 10.3389/fimmu.2017.00798. eCollection 2017.
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