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2009 年至 2013 年新加坡一家三级皮肤科中心酒渣鼻患者的临床特征和治疗。

Clinical characteristics and management of patients with rosacea in a tertiary dermatology center in Singapore from 2009 to 2013.

机构信息

National Skin Centre, Singapore.

Tan Tock Seng Hospital, Singapore.

出版信息

Int J Dermatol. 2018 May;57(5):541-546. doi: 10.1111/ijd.13954. Epub 2018 Feb 26.

Abstract

INTRODUCTION

Rosacea is a common chronic facial skin disease. A multiethnic society such as Singapore provides an opportunity to evaluate the demographic characteristics and their impact on clinical outcome in rosacea.

AIMS

The aim of this study was to evaluate characteristics and outcome of rosacea in a multiracial population in Singapore.

METHODS

Records of all rosacea patients between January 2009 and December 2013 were retrospectively retrieved from the electronic medical records (EMR). Descriptive analysis was performed to understand the characteristics of patients with rosacea. Multivariate logistic regression was used to evaluate the associations between the various variables and types of rosacea as well as the clinical outcome.

RESULTS

A total of 1340 patients were identified. The mean age at presentation was 42.8 years with a female predominance (65%). Most of the patients had erythematotelangiectatic rosacea (ETR) (56.3%) followed by papulopustular rosacea (PPR) (37%). With multinomial logistic regression, controlling for age, gender, and known triggers, Indians and Caucasians were more likely to have PPR compared to ETR (OR: 3.4, P = 0.01 and OR: 2.1, P = 0.01 respectively). Patients who had phymatous rosacea are also more likely to be older males (OR: 3.82 95% CI 1.64-8.92, P = 0.002).

CONCLUSION

The epidemiology and outcome of rosacea among local patients were studied. Rosacea is more common among certain racial groups such as Chinese, Caucasian, and other races. The clinical subtypes also seem to be related to races of certain skin colors and might be related to varied natural intrinsic responses to the sun among different racial groups.

摘要

简介

酒渣鼻是一种常见的慢性面部皮肤疾病。像新加坡这样的多种族社会为评估酒渣鼻的人口统计学特征及其对临床结果的影响提供了机会。

目的

本研究旨在评估新加坡多种族人群中酒渣鼻的特征和结局。

方法

从电子病历中回顾性检索 2009 年 1 月至 2013 年 12 月期间所有酒渣鼻患者的记录。进行描述性分析以了解酒渣鼻患者的特征。采用多元逻辑回归分析评估各种变量与酒渣鼻类型以及临床结局之间的关系。

结果

共确定了 1340 例患者。就诊时的平均年龄为 42.8 岁,女性居多(65%)。大多数患者为红斑毛细血管扩张型酒渣鼻(ETR)(56.3%),其次为丘疹脓疱型酒渣鼻(PPR)(37%)。多元逻辑回归分析表明,在控制年龄、性别和已知诱因的情况下,与 ETR 相比,印度人和白种人更有可能患有 PPR(OR:3.4,P = 0.01 和 OR:2.1,P = 0.01)。患有鼻赘型酒渣鼻的患者也更有可能是年龄较大的男性(OR:3.82 95%CI 1.64-8.92,P = 0.002)。

结论

研究了当地患者的酒渣鼻流行病学和结局。酒渣鼻在某些种族群体中更为常见,如华人、白种人和其他种族。临床亚型似乎也与某些肤色的种族有关,并且可能与不同种族对阳光的内在自然反应不同有关。

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