Schmalbach Cecelia E, Bradford Carol R
Department of Otolaryngology-Head & Neck Surgery Indiana University School of Medicine, Roudebush VA Medical Center Indianapolis Indiana U.S.A.
School of Medicine University of Michigan Ann Arbor Michigan U.S.A.
Laryngoscope Investig Otolaryngol. 2018 Feb 5;3(1):43-48. doi: 10.1002/lio2.136. eCollection 2018 Feb.
The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic intervention. Recent research to include large multi-institutional randomized trials have attempted to answer the question: is a completion lymph node dissection (CLND) required following a positive SLNB? This review provides an evidence-based, contemporary review of the utility of CLND for SLNB positive head and neck cutaneous melanoma patients.
NA.
自二十多年前黑色素瘤前哨淋巴结活检(SLNB)问世以来,其应用和效用已发生了显著演变。当前的重点已从一种分期方式转变为潜在的治疗干预措施。近期包括大型多机构随机试验在内的研究试图回答以下问题:前哨淋巴结活检阳性后是否需要进行根治性淋巴结清扫术(CLND)?本综述对根治性淋巴结清扫术在头颈部皮肤黑色素瘤前哨淋巴结活检阳性患者中的效用进行了基于证据的当代综述。
无。