Purvis Taylor E, De la Garza-Ramos Rafael, Abu-Bonsrah Nancy, Goodwin C Rory, Groves Mari L, Ain Michael C, Sciubba Daniel M
Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Department of Neurological Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, New York, NY, USA.
Clin Neurol Neurosurg. 2018 May;168:18-23. doi: 10.1016/j.clineuro.2018.02.005. Epub 2018 Feb 5.
To compare in-hospital complication rates in pediatric patients with atlantoaxial and subaxial injuries undergoing either external fixation or surgical fusion.
Baseline and outcome data were obtained from the 2002-2011 Nationwide Inpatient Sample (NIS) for patients under the age of 18 with a diagnosis of cervical spine fracture without spinal cord injury or cervical spine subluxation. Patients who underwent external immobilization or internal fixation were included for analysis. Variables analyzed included length of stay, in-hospital mortality, discharge disposition, total hospital charges, and development of at least one in-hospital complication.
A total of 2878 pediatric patients with cervical spine injury were identified; 1462 patients (50.8%) with atlantoaxial (C1-2) injury and 1416 (49.2%) with subaxial (C3-7) injury. Among atlantoaxial injury patients, external fixation was associated with lower total charges ($73,786 vs. $98,158, p = .040) and a lower likelihood of developing at least one complication (1.9% vs. 6.8%, p = .029) compared to surgical fusion, and was a more common treatment for subluxation alone (16.4% vs. 2.6%, p < .001). Among subaxial injury patients, there were no significant differences in age (p = .262), length of stay (p = .196), occurrence of at least one complication (p = .334), or total charges (p = .142). Subaxial subluxation injuries alone were treated more often with surgical fusion (2.2% vs. 1.2%, p < .001).
Optimal treatment of patients with cervical injury may vary by location of injury. Our findings warrant further investigation into the difference in clinical outcomes between surgical and non-surgical management of atlantoaxial and subaxial injury.
比较接受外固定或手术融合治疗的寰枢椎损伤和下颈椎损伤儿科患者的院内并发症发生率。
从2002 - 2011年全国住院患者样本(NIS)中获取18岁以下诊断为无脊髓损伤的颈椎骨折或颈椎半脱位患者的基线和结局数据。纳入接受外固定或内固定治疗的患者进行分析。分析的变量包括住院时间、院内死亡率、出院处置、总住院费用以及至少发生一种院内并发症的情况。
共确定2878例颈椎损伤儿科患者;1462例(50.8%)为寰枢椎(C1 - 2)损伤,1416例(49.2%)为下颈椎(C3 - 7)损伤。在寰枢椎损伤患者中,与手术融合相比,外固定的总费用较低(73,786美元对98,158美元,p = 0.040),且发生至少一种并发症的可能性较低(1.9%对6.8%,p = 0.029),并且单独半脱位时外固定是更常用的治疗方法(16.4%对2.6%,p < 0.001)。在下颈椎损伤患者中,年龄(p = 0.262)、住院时间(p = 0.196)、至少发生一种并发症的情况(p = 0.334)或总费用(p = 0.142)方面无显著差异。单独的下颈椎半脱位损伤更多采用手术融合治疗(2.2%对1.2%,p < 0.001)。
颈椎损伤患者的最佳治疗方法可能因损伤部位而异。我们的研究结果值得进一步调查寰枢椎和下颈椎损伤手术与非手术治疗的临床结局差异。