Department of Psychology, Queen's University, Kingston.
Department of Psychology, St. Joseph's Healthcare Hamilton.
J Affect Disord. 2018 Jul;234:1-7. doi: 10.1016/j.jad.2018.02.094. Epub 2018 Feb 27.
Major depressive disorder (MDD) is increasingly recognized as a disorder of everyday functioning. Multi-level approaches to investigating functioning have been employed in other conditions whereby competence (ability to perform living skills) is distinguished from real-world functioning, but not yet in MDD. We used a multidimensional (adaptive and interpersonal), multi-level (competence and performance) approach to investigate differences between those with MDD and healthy comparisons (HC) on measures of competence, functional disability, and self-perceived competence.
Between-group analysis of variance identified differences between MDD (n = 42) and HC (n = 24). Moderation analysis determined whether the strength of the relationship between competence accuracy and self-perception of performance was related to group membership.
In adaptive and interpersonal domains, the MDD group performed significantly lower on competence tasks, endorsed greater functional disability, and reported lower self-perception of competence. Group membership did not moderate the relationship between competence and self-perceived competence in the adaptive domain. Significant moderation was observed in the interpersonal domain such that competence and self-perception of abilities converged in the HC, but not MDD, group.
A cross-sectional design precluded the ability to interpret causality of results. Functional disability was measured by interview, thereby susceptible to biases in self-report.
A multi-level approach to assessing functioning in MDD was supported. Performance-based measures of functional competence are sensitive to MDD and useful for research trials and clinical work to objectively track everyday living skills. Objective measurement is further supported, as those with depression are less likely to accurately evaluate their own abilities, even after demonstrating skills.
重度抑郁症(MDD)日益被视为一种日常功能障碍。在其他疾病中,已经采用了多层次的方法来研究功能,将能力(执行生活技能的能力)与现实世界的功能区分开来,但在 MDD 中尚未采用。我们使用多维(适应性和人际关系)、多层次(能力和表现)的方法,研究了 MDD 患者(n=42)与健康对照组(HC)(n=24)在能力、功能障碍和自我感知能力方面的差异。
组间方差分析确定了 MDD 组(n=42)和 HC 组(n=24)之间的差异。调节分析确定了能力准确性和自我表现感知之间的关系强度是否与组别的关系。
在适应性和人际关系领域,MDD 组在能力任务上的表现明显较低,报告的功能障碍更大,自我感知能力较低。组别的归属并不能调节适应性领域中能力和自我感知能力之间的关系。在人际关系领域观察到显著的调节作用,即能力和自我感知能力在 HC 中趋于一致,但在 MDD 组中则不一致。
横断面设计排除了解释结果因果关系的能力。功能障碍通过访谈进行测量,因此容易受到自我报告的偏见。
支持对 MDD 进行功能评估的多层次方法。基于绩效的功能能力测量对 MDD 敏感,对研究试验和临床工作有用,可客观跟踪日常生活技能。进一步支持客观测量,因为即使表现出技能,抑郁症患者也不太可能准确评估自己的能力。