Department of Dermatology, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Institut de Recerca Biomèdica de Lleida (IRBLleida), University of Lleida, Lleida, Spain.
Pediatr Blood Cancer. 2018 Jul;65(7):e27047. doi: 10.1002/pbc.27047. Epub 2018 Mar 12.
Langerhans cell histiocytosis (LCH) is a disorder characterized by accumulation of Langerhans-like cells in one or various organs. A correct staging work-up is essential since there are multiorgan presentations with a poor prognosis. We report three patients with LCH skin lesions mimicking molluscum contagiosum in association with both high and low risk organ involvement. This peculiar cutaneous presentation can be a clue for the diagnosis of LCH, a disease with potentially severe systemic involvement.
朗格汉斯细胞组织细胞增生症(LCH)是一种以朗格汉斯样细胞在一个或多个器官中积聚为特征的疾病。由于存在多器官表现且预后不良,因此正确的分期检查至关重要。我们报告了 3 例 LCH 皮肤损害,其表现类似于传染性软疣,同时伴有高风险和低风险的器官受累。这种特殊的皮肤表现可能是 LCH 的诊断线索,LCH 是一种可能有严重全身受累的疾病。