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开放性颅缝早闭修复术的20年疗效经验:再手术率和并发症发生率分析

Twenty-Year Outcome Experience With Open Craniosynostosis Repairs: An Analysis of Reoperation and Complication Rates.

作者信息

Morrison Kerry A, Lee James C, Souweidane Mark M, Feldstein Neil A, Ascherman Jeffrey A

出版信息

Ann Plast Surg. 2018 Apr;80(4 Suppl 4):S158-S163. doi: 10.1097/SAP.0000000000001365.

Abstract

BACKGROUND

Surgical intervention during infancy for both syndromic and nonsyndromic patients with craniosynostosis remains the criterion standard of treatment with the 2 main options being open vault remodeling versus minimally invasive surgery. Although open cranial vault remodeling was initially considered a high-risk procedure, many advances have improved its safety. Despite this, there is a paucity of literature on the long-term outcomes of contemporary open craniosynostosis repair.

METHODS

A retrospective review of all patients who underwent primary open cranial vault repair for craniosynostosis by a single surgeon (J.A.A.) at New York-Presbyterian Hospital from 1995 to 2015 was performed.

RESULTS

For primary open repair, 81 patients (46 males, 35 females) were analyzed, and affected sutures included unicoronal (28), bicoronal (7), metopic (24), sagittal (11), lambdoid (2), and multisuture (9). Fourteen patients (17.3%) were syndromic. Mean (SD) operative patient age was 13.81 (16.24) months: 34 (42%) were 0 to 6 months; 26 (32%), 7 to 12 months; and 21 (26%), 12 months of age or older. There were no intraoperative complications. Mean (SD) estimated blood loss for the plastic surgery portion of all cases was 74.53 (72.34) mL, and total estimated blood loss was 174.93 (182.23) mL. Mean (SD) hospital length of stay was 4.31 (1.59) days. One syndromic patient was readmitted for a wound infection (1.2%) that was successfully treated with antibiotics, and 2 syndromic patients (2.5%) had reoperation for fronto-orbital readvancement.

CONCLUSIONS

This 20-year experience demonstrates the safety of modern open craniosynostosis repairs at a large academic medical center with low rates of mortality (0%), complications (1.2%), and reoperations (2.5%).

摘要

背景

对于患有颅缝早闭症的综合征型和非综合征型婴儿患者,手术干预仍然是治疗的标准方法,主要有两种选择,即开放性颅骨重塑和微创手术。尽管开放性颅骨重塑最初被认为是一种高风险手术,但许多进展提高了其安全性。尽管如此,关于当代开放性颅缝早闭修复术长期疗效的文献却很匮乏。

方法

对1995年至2015年在纽约长老会医院由单一外科医生(J.A.A.)进行原发性开放性颅骨修复治疗颅缝早闭症的所有患者进行回顾性研究。

结果

对于原发性开放性修复,分析了81例患者(46例男性,35例女性),受累缝线包括单冠状缝(28例)、双冠状缝(7例)、额缝(24例)、矢状缝(11例)、人字缝(2例)和多缝线(9例)。14例患者(17.3%)为综合征型。手术患者的平均(标准差)年龄为13.81(16.24)个月:34例(42%)为0至6个月;26例(32%)为7至12个月;21例(26%)为12个月及以上。术中无并发症。所有病例整形手术部分的平均(标准差)估计失血量为74.53(72.34)毫升,总估计失血量为174.93(182.23)毫升。平均(标准差)住院时间为4.31(1.59)天。1例综合征型患者因伤口感染再次入院(1.2%),经抗生素治疗成功,2例综合征型患者(2.5%)因额眶前移再次手术。

结论

这20年的经验表明,在大型学术医疗中心进行现代开放性颅缝早闭修复术具有安全性,死亡率低(0%)、并发症发生率低(1.2%)和再次手术率低(2.5%)。

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