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HIV感染中的结核病诊断与否

TB or not TB in HIV infection.

作者信息

Costache Diana Veronica, Isac Ina, Mihăescu Traian, Manciuc Carmen

出版信息

Pneumologia. 2016 Oct-Dec;65(4):210-1.

Abstract

The progression of tuberculosis (TB) is significantly faster in patients with HIV infection. TB is also the main cause of death for HIV-infected individuals, resulting in fatality for 1 of 3 patients. We present the case of a 26-year-old male who arrived at the hospital having previously been diagnosed with HIV in 2014, but was not compliant to the ARV treatment prescribed. The patient presented with acute onset of fever, cough, hemoptysis and malaise. Investigations such as sputum samples and a lymph node biopsy revealed the presence of M. tuberculosis in optic microscopy, which led to a diagnosis of pulmonary and ganglionary TB. As one of the first opportunistic infections that occur in HIV-infected individuals, TB may be one of the earliest clues of an HIV infection. Current guidelines recommend that all individuals diagnosed with HIV should also undertake testing for TB infections.

摘要

HIV感染患者的结核病进展明显更快。结核病也是HIV感染者的主要死因,导致三分之一的患者死亡。我们报告一例26岁男性病例,该患者于2014年被诊断出感染HIV,但未遵医嘱接受抗逆转录病毒治疗。患者出现发热、咳嗽、咯血和全身不适的急性发作。痰液样本和淋巴结活检等检查在光学显微镜下发现结核分枝杆菌,从而诊断为肺结核和淋巴结结核。作为HIV感染者最早出现的机会性感染之一,结核病可能是HIV感染的最早线索之一。当前指南建议,所有诊断为HIV的个体也应进行结核病感染检测。

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