Suppr超能文献

透析患者的特发性突发性感觉神经性聋。

Idiopathic sudden sensorineural hearing loss in dialysis patients.

机构信息

a Division of Nephrology, Department of Internal Medicine , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.

b Department of Otolaryngology-Head and Neck Surgery , Gangneung Asan Hospital, University of Ulsan College of Medicine , Gangneung , Korea.

出版信息

Ren Fail. 2018 Nov;40(1):170-174. doi: 10.1080/0886022X.2018.1450760.

Abstract

Although sudden sensorineural hearing loss (SSNHL) affects chronic kidney disease (CKD) patients more frequently than non-CKD patients, few reports have described SSNHL in dialysis patients. We aimed to review the characteristics of SSNHL in chronic dialysis patients and evaluate treatment responses to steroid therapy. We retrospectively reviewed the records of dialysis patients diagnosed with idiopathic SSNHL at Asan Medical Center between January 2000 and December 2014. Pure tone and speech audiometry analyzes were performed before and 2 weeks and 2 months after treatment onset to evaluate outcomes. Twenty-two patients (11 men, 11 women; mean age: 49.9 ± 11.7 years) were included; 16 (72%) and 6 (28%) had undergone hemodialysis and peritoneal dialysis, respectively, for a median of 49.2 ± 41.4 (1-144) months. End-stage renal disease was most frequently caused by diabetic nephropathy (11 cases), chronic glomerulonephritis (1 case) and unknown factors (7 cases). Common accompanying symptoms included tinnitus (68.2%), ear fullness (45.5%) and vertigo (27.3%). The mean pure tone audiometry threshold at the initial presentation was 82.6 ± 22.4 dB. At 2 months post-steroid treatment, 4 (18.2%), 4 (18.2%) and 6 (27.3%) patients exhibited a complete, partial, or slight recovery, respectively; 8 patients (36.3%) showed no improvement. Although we could not identify the specific cause of SSNHL in this population, our relatively large case series elucidates the precise clinical features of SSNHL in this population and demonstrates the outcomes of steroid treatment.

摘要

尽管突发性聋(SSNHL)在慢性肾脏病(CKD)患者中比非 CKD 患者更为常见,但鲜有报道描述透析患者的 SSNHL。我们旨在回顾慢性透析患者 SSNHL 的特征,并评估类固醇治疗的反应。我们回顾性分析了 2000 年 1 月至 2014 年 12 月期间在 Asan 医疗中心被诊断为特发性 SSNHL 的透析患者的病历。在治疗开始前、2 周和 2 个月时进行纯音和言语测听分析,以评估结果。共纳入 22 例患者(11 名男性,11 名女性;平均年龄:49.9±11.7 岁);16 例(72%)和 6 例(28%)分别接受血液透析和腹膜透析,中位数为 49.2±41.4(1-144)个月。终末期肾病最常见的病因是糖尿病肾病(11 例)、慢性肾小球肾炎(1 例)和原因不明(7 例)。常见的伴随症状包括耳鸣(68.2%)、耳闷(45.5%)和眩晕(27.3%)。初次就诊时的纯音测听阈值平均为 82.6±22.4dB。在类固醇治疗 2 个月后,4 例(18.2%)、4 例(18.2%)和 6 例(27.3%)患者分别完全、部分和轻度恢复;8 例(36.3%)患者无改善。虽然我们无法确定该人群 SSNHL 的具体病因,但我们的较大病例系列阐明了该人群 SSNHL 的精确临床特征,并显示了类固醇治疗的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b9/6014348/da8619334009/IRNF_A_1450760_F0001_B.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验