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肝素诱导的血小板减少继发上肢股青肿:病例报告

Upper Limb Phlegmasia Cerulea Dolens Secondary to Heparin-induced Thrombocytopenia: A Case Study.

作者信息

Gaines Matthew, Grant Mike, Robinson Simon, Stevenson Helene

机构信息

Department of Trauma and Orthopaedics, Bachelor of Medicine and Bachelor of Surgery, Aintree University Liverpool, Liverpool, England, United Kingdom.

出版信息

J Orthop Case Rep. 2017 Nov-Dec;7(6):55-58. doi: 10.13107/jocr.2250-0685.948.

Abstract

INTRODUCTION

Phlegmasia cerulea dolens (PCD) is a rare pathology with a very high morbidity and mortality rate, which usually occurs in the lower limb. There is very little literature available to aid management.

CASE REPORT

We present a case of upper limb PCD in a 67-year-old female secondary to heparin-induced thrombocytopenia caused by warfarin bridging. She presented to the orthopedic team with upper limb compartment syndrome from a bleed around a peripherally inserted central catheter, for which she was urgently taken to the theater for fasciotomies. Postoperatively, the patient's platelets dropped and the upper limb pain and swelling continued; after conservative management and anticoagulation failed the patient had an upper limb amputation of her right arm.

CONCLUSION

With limited guidelines and management options restricted by the large fasciotomy wounds, we believe amputation was the patients' best option.

摘要

引言

股青肿(PCD)是一种罕见的病症,发病率和死亡率极高,通常发生在下肢。目前几乎没有文献可用于辅助治疗。

病例报告

我们报告一例67岁女性上肢PCD病例,其病因是华法林桥接导致肝素诱导的血小板减少症。她因外周静脉置入中心静脉导管周围出血导致上肢骨筋膜室综合征而就诊于骨科团队,为此她被紧急送往手术室进行筋膜切开术。术后,患者血小板下降,上肢疼痛和肿胀持续;在保守治疗和抗凝治疗失败后,患者接受了右臂上肢截肢手术。

结论

由于指南有限且治疗选择受大的筋膜切开伤口限制,我们认为截肢是患者的最佳选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/5868885/f529118b055d/JOCR-7-55-g001.jpg

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