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一种预测全髋关节置换术后失血及输血风险的算法。

An algorithm for predicting blood loss and transfusion risk after total hip arthroplasty.

作者信息

Trevisan Carlo, Klumpp Raymond, Auriemma Laura, Compagnoni Riccardo

机构信息

Department of Orthopaedics and Traumatology, University of Milano-Bicocca, Italy; Department of Orthopaedics and Traumatology of the Hospital ASST Bergamo Est, Via Paderno 21, I-24068, Seriate, Bergamo, Italy.

Department of Orthopaedics and Traumatology of the Hospital ASST Bergamo Est, Via Paderno 21, I-24068, Seriate, Bergamo, Italy; ASST Bergamo Est, Via Paderno 21, I-24068, Seriate, Bergamo, Italy.

出版信息

Transfus Apher Sci. 2018 Apr;57(2):272-276. doi: 10.1016/j.transci.2018.03.006. Epub 2018 Mar 27.

Abstract

INTRODUCTION

Patients receiving blood transfusions after total hip arthroplasty have increased morbidity and longer lengths of stay compared to non-transfused patients. The aim of this study is to create an algorithm in order to identify patients at risk for transfusion after total hip replacement and define a safe point in hemoglobin levels after which the need for blood, transfusion can be excluded.

METHODS

This retrospective study analyzed hemoglobin (Hb) levels for 5 days in patients undergoing total hip replacement. An algorithm was implemented to identify the critical trends of Hb levels in the first two postoperative days, trying to identify the patients at high risk of transfusion. Specificity, sensibility and efficiency were calculated in relation to the capability of the algorithm to correctly identify transfused patients.

RESULTS

The algorithm found a pre-operative Hb ≥ 13 g/dl as a cut off between patients at low-risk or high-risk for transfusion. When parameters were calculated considering the best efficiency with the least number of false negatives, the algorithm showed a specificity of 84% and a sensitivity of 70% with an efficiency of 80.6%. Hb values >10 g/dl in the first operative day for low-risk patients and Hb level > 11 g/dl the second post-operative day for high-risk patients led to exclusion of the need for transfusion.

CONCLUSIONS

The algorithm suggested critical Hb levels to predict transfusion. In association with clinical data, the suggested critical values of Hb may be useful to schedule lab tests and a safe early discharge.

摘要

引言

与未接受输血的患者相比,全髋关节置换术后接受输血的患者发病率更高,住院时间更长。本研究的目的是创建一种算法,以识别全髋关节置换术后有输血风险的患者,并确定一个安全的血红蛋白水平点,在此水平之后可以排除输血需求。

方法

这项回顾性研究分析了接受全髋关节置换术患者5天内的血红蛋白(Hb)水平。实施了一种算法来识别术后前两天Hb水平的关键趋势,试图识别有高输血风险的患者。根据该算法正确识别输血患者的能力计算特异性、敏感性和效率。

结果

该算法发现术前Hb≥13g/dl是输血低风险或高风险患者之间的分界点。当考虑以最少假阴性数量获得最佳效率来计算参数时,该算法的特异性为84%,敏感性为70%,效率为80.6%。低风险患者在手术第一天Hb值>10g/dl以及高风险患者在术后第二天Hb水平>11g/dl可排除输血需求。

结论

该算法提出了预测输血的关键Hb水平。结合临床数据,建议的Hb临界值可能有助于安排实验室检查和安全早期出院。

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