智能手机应用支持下的孕期运动与营养：一项随机对照试验。

Pregnancy Exercise and Nutrition With Smartphone Application Support: A Randomized Controlled Trial.

机构信息

UCD Perinatal Research Centre, Obstetrics and Gynaecology, School of Medicine, the UCD Institute of Food and Health, UCD CSTAR, and the School of Public Health, Physical & Sports Sciences, Health Sciences Centre, University College Dublin, Dublin, the Department of Management & Marketing, University College Cork, Cork, and the Department of Endocrinology, St. Vincent's University Hospital, and the Department of Endocrinology, National Maternity Hospital, Dublin, Ireland.

出版信息

Obstet Gynecol. 2018 May;131(5):818-826. doi: 10.1097/AOG.0000000000002582.

DOI:10.1097/AOG.0000000000002582

PMID:29630009

Abstract

OBJECTIVE

To evaluate the effect of a healthy lifestyle package (an antenatal behavior change intervention supported by smartphone application technology) on the incidence of gestational diabetes mellitus (GDM) in overweight and obese women.

METHODS

Women with body mass indexes (BMIs) 25-39.9 were enrolled into this randomized controlled trial. The intervention consisted of specific dietary and exercise advice that addressed behavior change supported by a tailor-designed smartphone application. Women in the control group received usual care. The primary outcome was the incidence of GDM at 28-30 weeks of gestation. To reduce GDM from 15% to 7.2%, we estimated that 506 women would be required to have 80% power to detect this effect size at a significance of .05, that is, 253 in each group.

RESULTS

Between March 2013 and February 2016, 565 women were recruited with a mean BMI of 29.3 and mean gestational age of 15.5 weeks. The incidence of GDM did not differ between the two groups, 37 of 241 (15.4%) in the intervention group compared with 36 of 257 (14.1%) in the control group (relative risk 1.1, 95% CI 0.71-1.66, P=.71).

CONCLUSIONS

A mobile health-supported behavioral intervention did not decrease the incidence of GDM.

CLINICAL TRIAL REGISTRATION

ISRCTN registry, https://www.isrctn.com/, ISRCTN29316280.

摘要

目的

评估健康生活方式套餐（一种通过智能手机应用技术支持的产前行为改变干预）对超重和肥胖妇女中妊娠期糖尿病（GDM）发病率的影响。

方法

本随机对照试验纳入了 BMI 在 25-39.9 之间的女性。干预措施包括具体的饮食和运动建议，针对行为改变，并通过专门设计的智能手机应用程序提供支持。对照组的女性接受常规护理。主要结局是妊娠 28-30 周时 GDM 的发病率。为了将 GDM 的发病率从 15%降低到 7.2%，我们估计需要 506 名女性以 80%的效能在显著性水平为.05 时检测到这种效果大小，即每组 253 名。

结果

2013 年 3 月至 2016 年 2 月，共招募了 565 名平均 BMI 为 29.3 和平均妊娠 15.5 周的女性。两组的 GDM 发病率无差异，干预组 241 名女性中有 37 名（15.4%），对照组 257 名女性中有 36 名（14.1%）（相对风险 1.1，95%CI 0.71-1.66，P=.71）。