循环 microRNA 作为运动的新兴生物标志物。
Circulating microRNA as Emerging Biomarkers of Exercise.
机构信息
Department of Functional Biology (Physiology), University of Oviedo, Oviedo.
Biomedical Research Institute of Barcelona (IIBB)-CSIC.
出版信息
Exerc Sport Sci Rev. 2018 Jul;46(3):160-171. doi: 10.1249/JES.0000000000000148.
An interest has recently emerged in the role of circulating microRNAs (c-miRNAs) as posttranscriptional regulators, intercellular communicators and, especially, as potential biomarkers of the systemic response to acute exercise and training. We propose that, with the limited, heterogeneous, and mainly descriptive information currently available, c-miRNAs do not provide a reliable biomarker of exercise in healthy or diseased individuals.
最近人们对循环 microRNAs（c-miRNAs）的作用产生了兴趣，认为它们是转录后调控因子、细胞间通讯分子，尤其是作为急性运动和训练对全身反应的潜在生物标志物。我们提出，鉴于目前可用的信息有限、具有异质性且主要是描述性的，c-miRNAs 并不能为健康或患病个体的运动提供可靠的生物标志物。
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