Assaf Yazan, Nasser Maher, Jneid Hani, Ott David
Faculty of Medicine, Damascus University, Damascus, Syria.
Baylor College of Medicine, Houston, TX, USA.
Cardiol Ther. 2018 Jun;7(1):107-117. doi: 10.1007/s40119-018-0109-y. Epub 2018 Apr 17.
Right ventricular (RV) myxomas are extremely rare, but may have dreadful clinical sequelae including pulmonary embolism (PE). We present a case of a patient who had an RV myxoma that was attached to the tricuspid valve, and therefore could not be resected completely during surgery, and remnants of the tumor were seen on transthoracic echocardiogram during post-operative follow-up. Five months after surgery, the patient had PE, which could be due to tumor emboli or thromboemboli. Since repeat surgical resection was not feasible, the patient was started on warfarin. The patient is doing well and has had no PE recurrence over the past 20 months of follow-up. We have complemented the current case report with a comprehensive literature search and review on RV myxomas associated with PE in order to shed light on this uncommon but potentially lethal disorder. We concluded that right-sided cardiac myxomas, including RV myxomas, should be considered while dealing with PE, particularly in young patients with no risk factors, and that follow-up with echocardiography after surgery is important due to the possibility of recurrence, especially if complete resection was difficult to perform. Plain language summary available for this article.
右心室黏液瘤极为罕见,但可能会引发包括肺栓塞(PE)在内的严重临床后果。我们报告一例右心室黏液瘤患者,该肿瘤附着于三尖瓣,因此手术中无法完全切除,术后随访经胸超声心动图可见肿瘤残余。术后五个月,患者发生肺栓塞,可能是肿瘤栓子或血栓栓子所致。由于再次手术切除不可行,患者开始服用华法林。患者情况良好,在过去20个月的随访中未再发生肺栓塞。我们通过对与肺栓塞相关的右心室黏液瘤进行全面的文献检索和综述,补充了本病例报告,以阐明这种罕见但可能致命的疾病。我们得出结论,在处理肺栓塞时,应考虑右侧心脏黏液瘤,包括右心室黏液瘤,尤其是在无危险因素的年轻患者中;由于存在复发可能性,尤其是在难以进行完全切除的情况下,术后超声心动图随访很重要。本文提供通俗易懂的总结。