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开始使用激素避孕的年轻女性的健康相关生活质量:一项试点研究。

Health-related quality of life in young women starting hormonal contraception: a pilot study.

作者信息

Kristjánsdóttir Jóna, Sundelin Claes, Naessen Tord

机构信息

a Department of Women's and Children's Health, Obstetrics and Gynaecology , Uppsala University , Uppsala , Sweden.

出版信息

Eur J Contracept Reprod Health Care. 2018 Jun;23(3):171-178. doi: 10.1080/13625187.2018.1455179. Epub 2018 Apr 19.

Abstract

OBJECTIVES

Our purpose was to study whether there is a difference in self-rated health-related quality of life (HRQOL) and changes in HRQOL perception after 3 months of hormonal contraceptive use in adolescents. Seasonal variations in symptoms of depression were also studied.

METHODS

A test group (T1) (n = 193) and a selected control group (n = 238) of women aged 14-20 years who were visiting a young person's clinic completed the 36-item short-form health survey (SF-36) and answered additional questions on menstrual history and pattern, need for menstrual pain relief medication, and other regular medication. The test group was reassessed after 3 months of hormonal contraception (T2). Seasonal variations in reported SF-36 scores were studied for the whole group.

RESULTS

The selected control group and test group at T1 were similar with regard to age at menarche and menstrual pattern. The duration of bleeding and use of painkillers were significantly reduced and the impact on everyday life was significantly improved after 3 months of hormonal contraception (p = .000, two-tailed). No changes in HRQOL or symptoms of possible depression were found after 3 months of hormonal contraception. The highest prevalence odds ratio for possible depression (SF-36 mental health scale score ≤48), adjusted for group, season and age, for spring vs winter, was 2.15 (95% confidence interval 0.95, 4.85).

CONCLUSIONS

After 3 months of hormonal contraception both the number of days of menstrual bleeding and the use of medication to relieve menstrual pain were reduced, but there were no significant changes in self-rated HRQOL perception. Seasonal effects on HRQOL were reported.

摘要

目的

我们的目的是研究青少年使用激素避孕药3个月后,自我评估的健康相关生活质量(HRQOL)是否存在差异以及HRQOL认知的变化。同时还研究了抑郁症症状的季节性变化。

方法

一个测试组(T1)(n = 193)和一个选定的对照组(n = 238),由年龄在14 - 20岁、前往青少年诊所就诊的女性组成,她们完成了36项简短健康调查问卷(SF - 36),并回答了有关月经史和模式、缓解痛经药物需求以及其他常规用药的附加问题。测试组在使用激素避孕药3个月后进行重新评估(T2)。对整个组报告的SF - 36分数的季节性变化进行了研究。

结果

选定的对照组和T1时的测试组在初潮年龄和月经模式方面相似。使用激素避孕药3个月后,出血持续时间和止痛药的使用显著减少,对日常生活的影响显著改善(p = 0.000,双侧)。使用激素避孕药3个月后,未发现HRQOL或可能的抑郁症症状有变化。在对组、季节和年龄进行调整后,春季与冬季相比,可能患抑郁症(SF - 36心理健康量表得分≤48)的最高患病率比值比为2.15(95%置信区间0.95,4.85)。

结论

使用激素避孕药3个月后,月经出血天数和缓解痛经药物的使用均减少,但自我评估的HRQOL认知没有显著变化。报告了季节对HRQOL的影响。

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