男性生殖细胞分化的分子生物学特征。
Molecular biological features of male germ cell differentiation.
作者信息
Tanaka Hiromitsu, Hirose Mika, Tokuhiro Keizo, Tainaka Hitoshi, Miyagawa Yasushi, Tsujimura Akira, Okuyama Akihiko, Nishimune Yoshitake
机构信息
TANAKA Project, Center for Advanced Science and Innovation.
Department of Urology, Osaka University Graduate School of Medicine and.
出版信息
Reprod Med Biol. 2007 Feb 16;6(1):1-9. doi: 10.1111/j.1447-0578.2007.00158.x. eCollection 2007 Mar.
Abstract
Somatic cell differentiation is required throughout the life of a multicellular organism to maintain homeostasis. In contrast, germ cells have only one specific function; to preserve the species by conveying the parental genes to the next generation. Recent studies of the development and molecular biology of the male germ cell have identified many genes, or isoforms, that are specifically expressed in the male germ cell. In the present review, we consider the unique features of male germ cell differentiation. (Reprod Med Biol 2007; : 1-9).
摘要
在多细胞生物体的整个生命过程中，体细胞分化对于维持体内平衡是必需的。相比之下，生殖细胞只有一个特定功能，即通过将亲代基因传递给下一代来延续物种。最近对雄性生殖细胞发育和分子生物学的研究已经鉴定出许多在雄性生殖细胞中特异性表达的基因或异构体。在本综述中，我们探讨了雄性生殖细胞分化的独特特征。（《生殖医学与生物学》2007年；：1 - 9）
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