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脊髓损伤中钝性伤与穿透伤的比较:长期功能和神经学结果分析

Comparing Blunt and Penetrating Trauma in Spinal Cord Injury: Analysis of Long-Term Functional and Neurological Outcomes.

作者信息

Roach Mary Joan, Chen Yuying, Kelly Michael L

机构信息

Center for Healthcare Research and Policy, Case Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, Ohio.

Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham, Birmingham, Alabama.

出版信息

Top Spinal Cord Inj Rehabil. 2018 Spring;24(2):121-132. doi: 10.1310/sci2402-121.

Abstract

Comparisons between patients with penetrating spinal cord injury (PSCI) and blunt spinal cord injury (BSCI) are scarce. To describe baseline characteristics and neurological and functional outcomes for patients with BSCI and PSCI. Participants with BSCI ( = 5,316) and PSCI ( = 1,062) were extracted from the Spinal Cord Injury Model Systems database from January 1994 to January 2015. Participant injury and demographic characteristics were recorded. Outcomes were measured using the International Standards for Neurological Classification of Spinal Cord Injury and FIM motor scores. Outcomes for patients with American Spinal Injury Association Impairment Scale (AIS) complete injuries were analyzed separately from incomplete injuries at three time points: acute hospitalization, SCI rehabilitation, and 1-year follow-up. Patients with PSCI compared to those with BSCI were more likely to present with complete injuries (56.8% vs 35.9%; < .001) and were less likely to undergo spine surgery (19.6% vs 80.6%; < .001). For incomplete injuries, no significant differences were observed between groups in FIM scores or AIS grade improvement at 1 year. For complete injuries, patients with BSCI showed an increased one-grade (15.7% vs 9.1%; < .001) and three-grade (5.4% vs 1.9%; = .014) AIS improvement at 1 year. Multivariate regression analysis demonstrated an independent effect for BSCI on AIS improvement at 1 year (odds ratio [OR], 1.74; 95% CI, 1.13-2.70; C-stat = 0.66). Patient with PSCI had more complete injuries and lower surgery rates. Patients with complete BSCI show greater AIS improvement at 1 year, and incomplete injuries show no difference in neurological improvement between groups. Overall, patients with PSCI demonstrated worse functional outcomes at 1 year.

摘要

穿透性脊髓损伤(PSCI)患者与钝性脊髓损伤(BSCI)患者之间的比较很少见。目的是描述BSCI和PSCI患者的基线特征、神经学和功能结局。从1994年1月至2015年1月的脊髓损伤模型系统数据库中提取了BSCI患者(n = 5316)和PSCI患者(n = 1062)。记录了参与者的损伤和人口统计学特征。使用脊髓损伤神经学分类国际标准和FIM运动评分来测量结局。将美国脊髓损伤协会损伤量表(AIS)完全损伤患者的结局与三个时间点(急性住院、脊髓损伤康复和1年随访)的不完全损伤患者的结局分开进行分析。与BSCI患者相比,PSCI患者更有可能出现完全损伤(56.8%对35.9%;P <.001),并且接受脊柱手术的可能性更小(19.6%对80.6%;P <.001)。对于不完全损伤,两组在1年时的FIM评分或AIS分级改善方面未观察到显著差异。对于完全损伤,BSCI患者在1年时AIS改善一级(15.7%对9.1%;P <.001)和三级(5.4%对1.9%;P =.014)的比例增加。多变量回归分析表明,BSCI在1年时对AIS改善有独立影响(优势比[OR],1.74;95%置信区间,1.13 - 2.70;C统计量 = 0.66)。PSCI患者有更多的完全损伤和更低的手术率。完全性BSCI患者在1年时显示出更大的AIS改善,而不完全损伤患者在组间神经学改善方面无差异。总体而言,PSCI患者在1年时的功能结局更差。

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