在流通式微反应器中使用功能化整体聚合物/玻璃复合材料进行PASSflow合成。

PASSflow Syntheses Using Functionalized Monolithic Polymer/Glass Composites in Flow-Through Microreactors.

作者信息

Kirschning Andreas, Altwicker Carsten, Dräger Gerald, Harders Jan, Hoffmann Nora, Hoffmann Ulrich, Schönfeld Hagen, Solodenko Wladimir, Kunz Ulrich

机构信息

Institut für Organische Chemie der Universität Hannover Schneiderberg 1B 30167 Hannover (Germany) Fax: (+49) 511-762-3011.

Institut für Chemische Verfahrenstechnik der Technischen Universität Clausthal Leibnizstrasse 17, 38678 Clausthal-Zellerfeld (Germany) Fax: (+49) 5323-72-2182.

出版信息

Angew Chem Int Ed Engl. 2001 Nov 5;40(21):3995-3998. doi: 10.1002/1521-3773(20011105)40:21<3995::AID-ANIE3995>3.0.CO;2-V.

DOI:10.1002/1521-3773(20011105)40:21<3995::AID-ANIE3995>3.0.CO;2-V

PMID:29712229

Abstract

A chemistapos;s wish finally becomes reality: microreactors for every synthetic laboratory! By precipitation polymerization various polymers are introduced into the irregular pore system of a porous glass rod. By embedding these rods into a housing, followed by functionalization and immobilization of reagents onto the polymer phase, versatile microreactors are obtained. With this apparatus, chemical transformations in solution can be performed, for example, a steroid derivatization.

摘要