Zhang Xinghe, Guo Taipin, Zhu Bowen, Gao Qing, Wang Hourong, Tai Xiantao, Jing Fujie
School of Acupuncture-Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong School of Acupuncture-Tuina and Rehabilitation, Yunnan University of Traditional Chinese Medicine, Kunming, China.
Medicine (Baltimore). 2018 May;97(18):e0574. doi: 10.1097/MD.0000000000010574.
Preterm infants are babies born alive before 37 weeks. Many survived infants concomitant with defects of growth and development, a lifetime of disability usually as following when insufficient intervention. In early intervention of preterm infants, pediatric Tuina shows good effect in many Chinese and some English clinical trials. This systematic review is aimed to evaluate the efficacy and safety of pediatric Tuina for promoting growth and development of preterm infants.
The electronic databases of Cochrane Library, MEDLINE, EBASE, Web of Science, Springer, World Health Organization International Clinical Trials Registry Platform, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, Wan-fang database, Chinese Scientific Journal Database, and other databases will be searched from establishment to April 1, 2018. All published randomized controlled trials (RCTs) about this topic will be included. Two independent researchers will operate article retrieval, screening, quality evaluation, and data analyses by Review Manager (V.5.3.5). Meta-analyses, subgroup analysis, and/or descriptive analysis will be performed based on included data conditions.
High-quality synthesis and/or descriptive analysis of current evidence will be provided from weight increase, motor development, neuropsychological development, length of stay, days of weight recovery to birthweight, days on supplemental oxygen, daily sleep duration, and side effects.
This study will provide the evidence of whether pediatric Tuina is an effective early intervention for preterm infants.
There is no requirement of ethical approval and informed consent, and it will be in print or published by electronic copies.
This systematic review protocol has been registered in the PROSPERO network (No. CRD42018090563).
早产儿是指在37周前出生的活产婴儿。许多存活下来的婴儿伴有生长发育缺陷，如果干预不足，通常会终身残疾。在早产儿的早期干预中，小儿推拿在许多中文和一些英文临床试验中显示出良好的效果。本系统评价旨在评估小儿推拿促进早产儿生长发育的有效性和安全性。
检索Cochrane图书馆、MEDLINE、EBASE、Web of Science、Springer、世界卫生组织国际临床试验注册平台、中国知网、中国生物医学文献数据库、万方数据库、维普数据库等电子数据库，检索时间从建库至2018年4月1日。纳入所有发表的关于该主题的随机对照试验（RCT）。两名独立研究人员将通过Review Manager（V.5.3.5）进行文献检索、筛选、质量评估和数据分析。根据纳入的数据情况进行Meta分析、亚组分析和/或描述性分析。
将从体重增加、运动发育、神经心理发育、住院时间、恢复至出生体重的天数、吸氧天数、每日睡眠时间和副作用等方面提供当前证据的高质量综合和/或描述性分析。
本研究将提供小儿推拿是否是早产儿有效早期干预措施的证据。
本研究无需伦理批准和知情同意，将以印刷版或电子版形式发表。
本系统评价方案已在PROSPERO网络注册（注册号：CRD42018090563）。
Zotero 插件