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胸围、腰围和大腿围是痴呆症的预测指标。

Chest width, waist circumference, and thigh circumference are predictors of dementia.

机构信息

Department of Health Care Administration, Oriental Institute of Technology, New Taipei City, Taiwan.

Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.

出版信息

Int J Geriatr Psychiatry. 2018 Aug;33(8):1019-1027. doi: 10.1002/gps.4887. Epub 2018 May 4.

Abstract

OBJECTIVE

Few studies have investigated the relationship between specific body measures and dementia.

METHODS

Three-dimensional anthropometric body surface scanning data containing 38 body measures were collected from 6831 participants from the health examination department of a medical center in Taiwan during 2000 to 2008, and 236 dementia cases were identified during the 10-year follow-up. A multiple Cox regression analysis was performed.

RESULTS

Specific body measures, namely chest width (hazard ratio [HR] = 0.90; 95% confidence interval [CI] = 0.83-0.98), and right thigh circumference (HR = 0.93; 95% CI = 0.90-0.96), were protective predictors to dementia occurrence. Waist circumference (HR = 1.03; 95% CI = 1.02-1.05) was a risk factor in dementia occurrence. Among the combinations, dementia risk was higher in participants with a larger waist circumference and a smaller right thigh circumference, with the highest HR of 2.49 (95% CI = 1.54-4.03).

CONCLUSION

The body measures provide clues for future applications and scientific merits in both clinical and preventive medicine.

摘要

目的

鲜有研究调查特定身体测量指标与痴呆之间的关系。

方法

从 2000 年至 2008 年,我们从台湾一家医疗中心体检部门的 6831 名参与者中收集了包含 38 个体表测量指标的三维人体表面扫描数据,并在 10 年的随访中确定了 236 例痴呆病例。我们进行了多次 Cox 回归分析。

结果

特定的身体测量指标,即胸围(危险比 [HR] = 0.90;95%置信区间 [CI] = 0.83-0.98)和右大腿周长(HR = 0.93;95% CI = 0.90-0.96),是痴呆发生的保护预测因子。腰围(HR = 1.03;95% CI = 1.02-1.05)是痴呆发生的危险因素。在这些组合中,腰围较大且右大腿周长较小的参与者痴呆风险更高,最高 HR 为 2.49(95% CI = 1.54-4.03)。

结论

这些身体测量指标为未来在临床和预防医学中的应用和科学价值提供了线索。

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