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短暂性脑缺血发作或小卒中后的加速长期遗忘:检测隐匿性记忆功能障碍的更敏感指标?

Accelerated long-term forgetting after TIA or minor stroke: A more sensitive measure for detecting subtle memory dysfunction?

机构信息

Canisius Wilhelmina Hospital, Department of Medical Psychology, Nijmegen, The Netherlands.

University of Amsterdam, Department of Psychology, Brain and Cognition, Amsterdam, The Netherlands; OLVG, Department of Psychiatry and Medical Psychology, Amsterdam, The Netherlands; Rijnstate Hospital, Department of Medical Psychology, Arnhem, The Netherlands.

出版信息

Cortex. 2019 Jan;110:150-156. doi: 10.1016/j.cortex.2018.04.002. Epub 2018 Apr 12.

Abstract

Cognitive changes after minor stroke or TIA have been reported, with studies describing a 'vascular' cognitive profile with spared episodic memory. Still, many patients also report memory complaints. Studies using long-term forgetting paradigms have detected memory impairment after prolonged intervals in contrast to standard delayed testing in other patient groups. This study examined whether accelerated long-term forgetting (ALF) is present in patients with minor stroke or TIA by comparing one-week delayed recall and recognition with the performance of a healthy control group. Results revealed that the patients' performance after one week was worse than the controls, in the absence of an impairment after a short delay. Patients did, however, not report more memory worries than controls. Possibly, reduced effort, attention or mnemonic strategies may contribute to subtle consolidation problems, which go undetected in daily functioning.

摘要

据报道,轻度中风或 TIA 后会出现认知变化,研究描述了一种“血管性”认知特征,伴有情景记忆不受影响。尽管如此,许多患者仍会报告记忆问题。使用长期遗忘范式的研究在与其他患者群体的标准延迟测试相比的情况下,在长时间间隔后检测到记忆损伤。本研究通过比较一周后的延迟回忆和识别与健康对照组的表现,来检查轻度中风或 TIA 患者是否存在加速长期遗忘 (ALF)。结果表明,患者在一周后的表现比对照组差,而在短延迟后没有出现损伤。然而,患者并没有比对照组报告更多的记忆问题。可能是由于注意力或记忆策略的减少导致了细微的巩固问题,这些问题在日常功能中未被发现。

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