Agrawal Swastik, Rana Baldev S, Mitra Suvradeep, Duseja Ajay, Das Ashim, Dhiman Radha K, Chawla Yogesh
Department of Hepatology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
J Clin Exp Hepatol. 2018 Mar;8(1):95-97. doi: 10.1016/j.jceh.2017.08.006. Epub 2017 Sep 1.
Acute on Chronic Liver Failure (ACLF) is an acute worsening of patients with chronic liver disease resulting in liver failure. Usually these patients have cirrhosis as the underlying liver disease with alcohol being the most common etiology. Common hepatitic illnesses causing acute worsening in Indian patients of ACLF include alcoholic hepatitis, acute viral hepatitis related to hepatitis E virus and acute flare in chronic hepatitis B. We report an adult case of ACLF due acute viral hepatitis related to hepatitis A virus infection superimposed on nonalcoholic steatohepatitis without cirrhosis.
慢加急性肝衰竭(ACLF)是慢性肝病患者出现急性恶化并导致肝衰竭。通常这些患者以肝硬化作为潜在的肝脏疾病,酒精是最常见的病因。在印度慢加急性肝衰竭患者中,导致急性恶化的常见肝病包括酒精性肝炎、与戊型肝炎病毒相关的急性病毒性肝炎以及慢性乙型肝炎急性发作。我们报告一例成年慢加急性肝衰竭病例,其由甲型肝炎病毒感染相关的急性病毒性肝炎叠加在非酒精性脂肪性肝炎(无肝硬化)基础上所致。