Malik Devin, Handa Richa, Petraszko Andrew, Tejwani Sheela
Department of Hematology Oncology, Henry Ford Hospital, 2799 W. Grand Blvd., Detroit, MI 48202, USA.
Department of Internal Medicine, Henry Ford Allegiance Health, 205 N. East Ave., Jackson, MI 49201, USA.
Case Rep Rheumatol. 2018 Mar 20;2018:3168452. doi: 10.1155/2018/3168452. eCollection 2018.
SAPHO syndrome is a rare clinical entity composed of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO). We describe a case of SAPHO syndrome masquerading as metastatic breast cancer in a patient with localized breast cancer who presented with cord compression. There was no pathologic evidence of metastatic cancer; however, a bone scan indicated osseous involvement. After multidisciplinary review of images and with additional findings of pustulosis and acne, a clinical diagnosis of SAPHO was made.
滑膜炎、痤疮、脓疱病、骨肥厚和骨炎综合征(SAPHO综合征)是一种罕见的临床病症。我们描述了一例局部乳腺癌患者发生脊髓压迫,其SAPHO综合征伪装成转移性乳腺癌。没有转移性癌症的病理证据;然而,骨扫描显示有骨受累。在对影像进行多学科评估并发现脓疱病和痤疮的其他表现后,做出了SAPHO综合征的临床诊断。