使用单光子发射计算机断层扫描对亨廷顿舞蹈病患者脑血流标志物进行成像
Imaging of cerebral blood flow markers in Huntington's disease using single photon emission computed tomography.
作者信息
Reid I C, Besson J A, Best P V, Sharp P F, Gemmell H G, Smith F W
机构信息
Department of Mental Health, University of Aberdeen, Foresterhill, UK.
出版信息
J Neurol Neurosurg Psychiatry. 1988 Oct;51(10):1264-8. doi: 10.1136/jnnp.51.10.1264.
Abstract
Single photon emission computed tomography (SPECT) imaging of six Huntington's disease patients revealed a striking reduction in regional uptake of cerebral blood flow markers in vivo. Similar changes were found in one patient with "early stage" disease. The findings are compared with parallel magnetic resonance imaging (MRI) studies, and in one case, results of postmortem examination.
摘要
对六名亨廷顿舞蹈症患者进行的单光子发射计算机断层扫描（SPECT）成像显示，活体中脑血流标志物的局部摄取显著减少。在一名“早期”疾病患者中也发现了类似变化。将这些发现与平行的磁共振成像（MRI）研究结果进行了比较，并在一个病例中与尸检结果进行了比较。
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