Laboratory of Neuroimaging, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20892.
Laboratory of Neuroimaging, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda 20892, Maryland, USA.
Front Biosci (Landmark Ed). 2018 Jun 1;23(12):2255-2266. doi: 10.2741/4704.
Sugar is highly palatable and rewarding, both in its taste and nutritive input. Excessive sugar consumption, however, may trigger neuroadaptations in the reward system that decouple eating behavior from caloric needs and leads to compulsive overeating. Excessive sugar intake is in turn associated with adverse health conditions, including obesity, metabolic syndrome, and inflammatory diseases. This review aims to use recent evidence to connect sugar's impact on the body, brain, and behavior to elucidate how and why sugar consumption has been implicated in addictive behaviors and poor health outcomes.
糖具有极高的可口性和奖赏性,无论是在口味还是营养摄入方面。然而,过量的糖消费可能会引发奖励系统的神经适应,使进食行为与热量需求脱钩,导致强迫性过度进食。过量的糖摄入反过来又与不良健康状况有关,包括肥胖、代谢综合征和炎症性疾病。本综述旨在利用最新证据将糖对身体、大脑和行为的影响联系起来,阐明为什么糖的消费与成瘾行为和不良健康结果有关。