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恶性黑色素瘤的组织学模仿物。

Histologic mimics of malignant melanoma.

作者信息

Bsirini Caroline, Smoller Bruce R

机构信息

Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.

出版信息

Singapore Med J. 2018 Nov;59(11):602-607. doi: 10.11622/smedj.2018041. Epub 2018 May 18.

Abstract

Although spongiotic (eczematous), psoriatic and cutaneous skin infections are among the most common in dermatology consultations, melanocytic lesions - including the different types of nevi and melanomas - are among those that cause a great deal of concern and stress to patients and their clinicians. A diagnosis of benign melanocytic nevus carries a very good prognosis. However, a diagnosis of melanoma might indicate more aggressive treatment, lifelong surveillance and a worse prognosis. Differentiating between these conditions is not always a straightforward process for clinicians and pathologists. Therefore, knowledge of melanoma mimickers is very important for clinicians in general, and dermatologists and pathologists in particular. In this review, we called attention to some of the more frequent benign but unusual melanocytic lesions that are of diagnostic concern for clinicians evaluating these cutaneous proliferations.

摘要

尽管海绵状(湿疹样)、银屑病样和皮肤感染是皮肤科会诊中最常见的病症,但黑素细胞性病变——包括不同类型的痣和黑色素瘤——却是令患者及其临床医生极为担忧和倍感压力的病变类型。诊断为良性黑素细胞痣的预后非常好。然而,诊断为黑色素瘤可能意味着需要更积极的治疗、终身监测且预后较差。对临床医生和病理学家而言,区分这些病症并非总是一个简单直接的过程。因此,了解黑色素瘤的模仿者对一般临床医生,尤其是皮肤科医生和病理学家非常重要。在本综述中,我们提请注意一些更常见的良性但不寻常的黑素细胞性病变,这些病变在评估这些皮肤增生的临床医生的诊断中备受关注。

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