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波利诺山地区(意大利南部巴斯利卡塔大区)天然存在的石棉纤维对健康的影响

[Health impact of asbestos fibres naturally occurring in Mount Pollino area (Basilicata Region, Southern Italy)].

作者信息

Caputo Angelo, De Santis Marco, Manno Valerio, Cauzillo Gabriella, Bruni Biagio Maria, Palumbo Lorenzo, Conti Susanna, Comba Pietro

机构信息

Azienda sanitaria locale, Potenza.

Dipartimento ambiente e salute, Istituto superiore di sanità, Roma.

出版信息

Epidemiol Prev. 2018 Mar-Apr;42(2):142-150. doi: 10.19191/EP18.2.P142.043.

Abstract

OBJECTIVES

to estimate the health impact of asbestos fibres naturally occurring in Mount Pollino area (Basilicata Region, Southern Italy).

DESIGN

geographic mortality, hospitalization, and incidence study. Setting and participant s: population resident in 12 Municipalities of Mount Pollino area with naturally occurring asbestos fibres.

MAIN OUTCOME MEASURES

standardized mortality ratio (SMR) and standardized hospitalization rate (SHR) for asbestos-related diseases; standardized incidence ratio (SIR) for mesotheliomas. Result s: in the area of Mount Pollino, where asbestos fibres naturally occur, especially in the sub-area in which fibres are close to dwellings and settlements, it was observed: • a significant excess of mesothelioma incidence (SIR: 208; CI95% 111-355; 13 observed); • a non-significant excess of hospitalization for malignant pleural neoplasms (SHR: 176; CI95% 93-335; 9 observed); • a significant excess for mortality and hospitalization for pneumoconiosis (SMR: 534; CI95% 345-824; 20 observed - SHR: 245; CI95% 149-405; 15 observed); • a significant excess for hospitalization (SHR: 852; CI95% 290-2,506; 3 observed) for asbestosis.

CONCLUSION

it is necessary to continue environmental monitoring and environmental remediation in the area with higher asbestos exposure. It is suggested to implement a permanent process of epidemiological surveillance in this same area. A communication plan with local administrators, general practitioners, school teachers, media, and the resident population at large should be realized.

摘要

目的

评估波利诺山地区(意大利南部巴斯利卡塔大区)天然存在的石棉纤维对健康的影响。

设计

地理死亡率、住院率及发病率研究。地点与参与者:居住在波利诺山地区12个存在天然石棉纤维的市镇的居民。

主要观察指标

石棉相关疾病的标准化死亡率(SMR)和标准化住院率(SHR);间皮瘤的标准化发病率(SIR)。结果:在天然存在石棉纤维的波利诺山地区,尤其是纤维靠近住宅和定居点的子区域,观察到:•间皮瘤发病率显著过高(SIR:208;95%置信区间111 - 355;观察到13例);•恶性胸膜肿瘤住院率无显著过高(SHR:176;95%置信区间93 - 335;观察到9例);•尘肺病死亡率和住院率显著过高(SMR:534;95%置信区间345 - 824;观察到20例 - SHR:245;95%置信区间149 - 405;观察到15例);•石棉沉着病住院率显著过高(SHR:852;95%置信区间290 - 2506;观察到3例)。

结论

有必要继续对石棉暴露较高地区进行环境监测和环境整治。建议在该地区实施永久性的流行病学监测程序。应制定一项与当地行政人员、全科医生、学校教师、媒体以及广大居民的沟通计划。

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