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基于关键帧提取的骨盆CT图像中的骨骼分割

The segmentation of bones in pelvic CT images based on extraction of key frames.

作者信息

Yu Hui, Wang Haijun, Shi Yao, Xu Ke, Yu Xuyao, Cao Yuzhen

机构信息

Department of Biomedical Engineering, Tianjin University, Tianjin, China.

Department of Orthopedic, Tianjin Medical University General Hospital, Tianjin, China.

出版信息

BMC Med Imaging. 2018 May 22;18(1):18. doi: 10.1186/s12880-018-0260-x.

Abstract

BACKGROUND

Bone segmentation is important in computed tomography (CT) imaging of the pelvis, which assists physicians in the early diagnosis of pelvic injury, in planning operations, and in evaluating the effects of surgical treatment. This study developed a new algorithm for the accurate, fast, and efficient segmentation of the pelvis.

METHODS

The proposed method consists of two main parts: the extraction of key frames and the segmentation of pelvic CT images. Key frames were extracted based on pixel difference, mutual information and normalized correlation coefficient. In the pelvis segmentation phase, skeleton extraction from CT images and a marker-based watershed algorithm were combined to segment the pelvis. To meet the requirements of clinical application, physician's judgment is needed. Therefore the proposed methodology is semi-automated.

RESULTS

In this paper, 5 sets of CT data were used to test the overlapping area, and 15 CT images were used to determine the average deviation distance. The average overlapping area of the 5 sets was greater than 94%, and the minimum average deviation distance was approximately 0.58 pixels. In addition, the key frame extraction efficiency and the running time of the proposed method were evaluated on 20 sets of CT data. For each set, approximately 13% of the images were selected as key frames, and the average processing time was approximately 2 min (the time for manual marking was not included).

CONCLUSIONS

The proposed method is able to achieve accurate, fast, and efficient segmentation of pelvic CT image sequences. Segmentation results not only provide an important reference for early diagnosis and decisions regarding surgical procedures, they also offer more accurate data for medical image registration, recognition and 3D reconstruction.

摘要

背景

骨盆的骨分割在骨盆计算机断层扫描(CT)成像中很重要,有助于医生早期诊断骨盆损伤、规划手术以及评估手术治疗效果。本研究开发了一种用于准确、快速且高效地分割骨盆的新算法。

方法

所提出的方法主要由两个部分组成:关键帧提取和骨盆CT图像分割。基于像素差异、互信息和归一化相关系数提取关键帧。在骨盆分割阶段,将从CT图像中提取骨骼与基于标记的分水岭算法相结合来分割骨盆。为满足临床应用需求,需要医生进行判断。因此,所提出的方法是半自动的。

结果

本文使用5组CT数据测试重叠区域,并使用15张CT图像确定平均偏差距离。5组的平均重叠面积大于94%,最小平均偏差距离约为0.58像素。此外,在20组CT数据上评估了所提出方法的关键帧提取效率和运行时间。对于每组数据,大约13%的图像被选为关键帧,平均处理时间约为2分钟(不包括手动标记时间)。

结论

所提出的方法能够实现骨盆CT图像序列的准确、快速且高效的分割。分割结果不仅为早期诊断和手术决策提供重要参考,还为医学图像配准、识别和三维重建提供更准确的数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4be/5964913/b4ce5ff3096c/12880_2018_260_Fig1_HTML.jpg

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