Oskovi Kaplan Zeynep Aslı, Şirvan Ali Levent, Topçu Hasan Onur
Department of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women's Health Research and Practice Center, University of Health Sciences, Ankara, Turkey.
Department of Pathology, Dr. Zekai Tahir Burak Women's Health Research and Practice Center, University of Health Sciences, Ankara, Turkey.
J Exp Ther Oncol. 2018 May;12(3):207-210.
Incidence of molar pregnancy is 1-3/1000 pregnancies. Invasive mole is a local invasive form of gestational trophoblastic neoplasias which is mostly seen in reproductive age and usually follows a molar pregnancy and rarely has an initial presentation. Ectopic pregnancy in rudimentary uterine horn is extremely rare and is seen in 1/100,000 - 140,000 pregnancies. Invasive mole has seldom been reported in ectopic localizations but not in a patient with Müllerian duct anomaly. Here we represent a case of invasive mole in a reproductive age patient with unicornuate uterus and rudimentary communicating uterine horn. Invasive mole presented initially, mimicking ectopic pregnancy. The patient underwent diagnostic laparoscopy and resection of rudimentary uterine horn was performed. The pathology result was reported as an invasive mole. Serum b-hCG levels normalized on post-operative first month and no additional chemotherapy was needed.
葡萄胎的发病率为每1000次妊娠中有1 - 3例。侵蚀性葡萄胎是妊娠滋养细胞肿瘤的一种局部侵袭性形式,多见于育龄期,通常继发于葡萄胎之后,很少有初始表现。残角子宫妊娠极为罕见,在每100,000 - 140,000次妊娠中可见1例。侵蚀性葡萄胎很少在异位部位报道,但未见于苗勒管异常患者。在此,我们报告1例育龄期单角子宫合并残角子宫且有交通的患者发生侵蚀性葡萄胎的病例。侵蚀性葡萄胎最初表现类似异位妊娠。患者接受了诊断性腹腔镜检查并切除了残角子宫。病理结果报告为侵蚀性葡萄胎。术后第一个月血清β - hCG水平恢复正常,无需额外化疗。