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心脏内装置的侵袭性李斯特菌病

Invasive Listeriosis of Intracardiac Device.

作者信息

Sharma Prerna, Yassin Mohamed

机构信息

Internal Medicine Resident, UPMC Mercy, Pittsburgh, PA, USA.

Infectious Diseases, UPMC Mercy, Pittsburgh, PA, USA.

出版信息

Case Rep Med. 2018 Apr 17;2018:1309037. doi: 10.1155/2018/1309037. eCollection 2018.

Abstract

INTRODUCTION

is a food-borne pathogen which can cause invasive infection in immunocompromised adults. Listeria has been known to cause infections during pregnancy and in older adults. Listeria endocarditis is a rare condition. A case of listeria-related intracardiac device infection is reported below.

CASE REPORT

A 74-year-old male with a past medical history of coronary artery disease, congestive cardiac failure, permanent atrial fibrillation status after nodal ablation, and placement of a biventricular pacemaker presented to the hospital with complaints of generalized fatigue. He was found to have listeria bacteremia, and transthoracic echocardiogram (TTE) showed pacemaker lead vegetation. The patient was treated with 6 weeks of vancomycin followed by oral suppression with amoxicillin.

DISCUSSION

Listeria can affect native valves, prosthetic valves, or nonvalvular intracardiac devices. The mean age of prosthetic valve endocarditis has been reported to be 67 years with male-to-female ratio 1.7 : 1 and mitral-to-aortic valve ratio 1.3 : 1. There have been case reports of listeria prosthetic valve endocarditis; however, there is paucity of literature on listeria-related pacemaker lead infection. Treatment is mostly a combination of penicillin and aminoglycosides for 4-6 weeks. Surgical removal of the infected device is preferred. Invasive listeriosis is a rare but fatal entity which should be identified and treated promptly to ensure a good outcome.

摘要

引言

李斯特菌是一种食源性病原体,可在免疫功能低下的成年人中引起侵袭性感染。已知李斯特菌会在孕期和老年人中引发感染。李斯特菌性心内膜炎是一种罕见病症。下文报告了一例与李斯特菌相关的心内装置感染病例。

病例报告

一名74岁男性,有冠状动脉疾病、充血性心力衰竭、结性消融术后永久性心房颤动病史,且植入了双心室起搏器,因全身乏力前来就诊。发现他患有李斯特菌血症,经胸超声心动图(TTE)显示起搏器导线赘生物。患者接受了6周的万古霉素治疗,随后用阿莫西林进行口服抑制治疗。

讨论

李斯特菌可影响天然瓣膜、人工瓣膜或非瓣膜性心内装置。据报道,人工瓣膜心内膜炎的平均年龄为67岁,男女比例为1.7∶1,二尖瓣与主动脉瓣比例为1.3∶1。有关于李斯特菌性人工瓣膜心内膜炎的病例报告;然而,关于与李斯特菌相关的起搏器导线感染的文献较少。治疗大多采用青霉素和氨基糖苷类药物联合使用4至6周。首选手术取出感染装置。侵袭性李斯特菌病是一种罕见但致命的疾病,应及时识别并治疗以确保良好预后。

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