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一种评估A型肉毒杆菌毒素治疗鱼尾纹后皮肤纹理粗糙度改善情况的客观方法。

An objective method to assess the improvements of skin texture roughness after botulinum toxin type a treatment of crow's feet.

作者信息

Cavallini M, Papagni M, Gazzola R

机构信息

Department of Dermatosurgery and Aesthetic Medicine, CDI Hospital, Milan, Italy.

Plastic Surgery Department, Policlinico di Monza, Monza, Italy.

出版信息

Skin Res Technol. 2019 Jan;25(1):54-59. doi: 10.1111/srt.12595. Epub 2018 Jun 6.

Abstract

BACKGROUND

Photo-numeric scales could lack precision and objectivity on evaluating the improvements on wrinkles after a treatment with botulinum toxin type A. The authors suggest a new digital evaluation method to analyze its effectiveness.

OBJECTIVES

This study aims to investigate retrospectively the effect of intramuscular injection of botulinum toxin type A on skin texture in the lateral peri-orbital region with a new objective method.

METHODS

Skin texture roughness (STR) in the lateral peri-orbital region is evaluated with a multi-directional light beam by light emitting diodes of different wavelengths (Antera 3D ), before and after injections of 12 units of botulinum toxin type A. The wrinkles and lines deeper than 0.5 mm are filtered to measure accurately skin texture.

RESULTS

We observed an improvement of STR in all cases treated with botulinum toxin type A. A significant decrease of STR was recorded as follows: 17.08% (P < .0001) at 4 weeks and 12.14% at 4 months (P = .001).

CONCLUSION

Botulinum toxin type A treatment of crow's feet was able to improve STR. The Antera device and software are a valuable, objective, easy and reproducible method to assess the effects of the toxin.

摘要

背景

在评估A型肉毒毒素治疗后皱纹的改善情况时,照片数字评分量表可能缺乏准确性和客观性。作者提出了一种新的数字评估方法来分析其有效性。

目的

本研究旨在采用一种新的客观方法,回顾性研究肌内注射A型肉毒毒素对眶周外侧区域皮肤质地的影响。

方法

在注射12单位A型肉毒毒素前后,使用不同波长发光二极管的多方向光束(Antera 3D)评估眶周外侧区域的皮肤质地粗糙度(STR)。对深度超过0.5毫米的皱纹和纹路进行过滤,以准确测量皮肤质地。

结果

我们观察到所有接受A型肉毒毒素治疗的病例中STR均有改善。STR显著降低如下:4周时为17.08%(P <.0001),4个月时为12.14%(P =.001)。

结论

A型肉毒毒素治疗鱼尾纹能够改善STR。Antera设备和软件是评估毒素效果的一种有价值、客观、简便且可重复的方法。

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