成功的静脉注射脂质乳剂治疗：奥氮平中毒。

Successful intravenous lipid emulsion therapy: Olanzapine intoxication.

作者信息

Yeniocak S, Kalkan A, Metin D D, Demirel A, Sut R, Akkoc I

机构信息

Haseki Training and Research Hospital, Department of Emergency Medicine, Istanbul, Turkey.

出版信息

Acute Med. 2018;17(2):96-97.

PMID:29882560

Abstract

Olanzapine is an antipsychotic drug used in psychiatric diseases. At high doses it exhibits cardiovascular and neurological sideeffects in particular. Lipid emulsion therapy for the removal of medication from plasma in high-dose lipophilic drug use has recently become very widespread. In the light of current literature, this report discusses the successful treatment of a patient within 4 hrs of olanzapine overdose as an attempted suicide, who presented with agitation and clouded consciousness.

摘要

奥氮平是一种用于治疗精神疾病的抗精神病药物。高剂量使用时，它尤其会出现心血管和神经方面的副作用。近年来，脂质乳剂疗法在高剂量亲脂性药物使用中用于从血浆中清除药物的应用变得非常广泛。根据当前文献，本报告讨论了一名因过量服用奥氮平企图自杀的患者的成功治疗案例，该患者出现躁动和意识模糊，在4小时内得到救治。