Gittens Paul, Mullen Gregory
a Philadelphia Center for Sexual Medicine , Philadelphia, PA , USA.
b Drexel University College of Medicine , Philadelphia, PA , USA.
J Cosmet Laser Ther. 2019;21(3):127-131. doi: 10.1080/14764172.2018.1481510. Epub 2018 Jun 8.
To examine the outcomes of sexual function in postmenopausal women and women with a history of breast cancer treated with endocrine therapy who were experiencing the symptoms of GSM for which they were treated with fractional microablative CO laser.
From July 2015 to October 2016, a retrospective chart review of women who underwent fractional microablative CO laser therapy (MonaLisa Touch, DEKA) for GSM was conducted. Several validated questionnaires were used to assess changes in symptoms and sexual function including the Female Sexual Function Index (FSFI), the Wong-Baker Faces Scale (WBFS), and the Female Sexual Distress Scale-Revised (FSDSR). Comparisons of mean symptom scores were described at baseline and six weeks after each treatment.
There was a statistically significant improvement in every domain of FSFI, WBFS, and FSDS-R when comparing baseline symptom scores to after treatment three symptom scores for all patients. The secondary outcome was to evaluate the differences, if any, in outcomes of sexual function between postmenopausal women and women with a history of breast cancer treated with endocrine therapy. Both groups had statistically significant improvements in many domains studied.
Fractional microablative CO laser therapy (MonaLisa Touch, DEKA) is an effective modality in treating the symptoms of GSM in postmenopausal women and women with a history of breast cancer treated with endocrine therapy.
研究接受内分泌治疗且患有更年期泌尿生殖道综合征(GSM)症状并接受分次微消融二氧化碳激光治疗的绝经后女性和有乳腺癌病史女性的性功能结局。
2015年7月至2016年10月,对接受分次微消融二氧化碳激光治疗(黛卡公司的蒙娜丽莎触摸治疗)的GSM女性进行回顾性病历审查。使用了几种经过验证的问卷来评估症状和性功能的变化,包括女性性功能指数(FSFI)、面部表情疼痛量表(WBFS)和修订后的女性性困扰量表(FSDSR)。在每次治疗的基线和六周后描述平均症状评分的比较。
将所有患者的基线症状评分与治疗后三个症状评分进行比较时,FSFI、WBFS和FSDS-R的每个领域均有统计学上的显著改善。次要结果是评估绝经后女性和接受内分泌治疗的有乳腺癌病史女性在性功能结局方面的差异(如有)。两组在许多研究领域均有统计学上的显著改善。
分次微消融二氧化碳激光治疗(黛卡公司的蒙娜丽莎触摸治疗)是治疗绝经后女性和接受内分泌治疗的有乳腺癌病史女性GSM症状的有效方式。