Ganeshan Muniswaran, Bujang Mohamad Adam, Soelar Shahrul Aiman, Karalasingam Shamala Devi, Suharjono Harris, Jeganathan Ravichandran
Sarawak General Hospital, Ministry of Health Malaysia, Kuching, Sarawak Malaysia.
Clinical Research Centre, Sarawak General Hospital, Jalan Hospital, Ministry of Health Malaysia, 93586 Kuching, Sarawak Malaysia.
J Obstet Gynaecol India. 2018 Jun;68(3):173-178. doi: 10.1007/s13224-017-1000-9. Epub 2017 May 4.
The aim of this study is to compare obstetric outcomes between overweight and class 1 obesity among pregnant women in their first pregnancy based on WHO's BMI cut-offs and the potential public health action points identified by WHO expert consultations specific for high-risk population such as Asians.
This is a retrospective cohort review of data obtained from the Malaysian National Obstetrics and Gynaecology Registry between the year 2010 and year 2012. All women in their first pregnancy with a booking BMI in their first trimester were included in this study. The association between BMI classifications as defined by the WHO cut-offs and the potential public health action points identified by WHO expert consultations towards adverse obstetric outcomes was compared.
A total of 88,837 pregnant women were included in this study. We noted that the risk of adverse obstetric outcomes was significantly higher using the public health action points identified by WHO expert consultations even among the overweight group as the risk of stillbirths was (OR 1.2; 95% CI 1.0,1.4), shoulder dystocia (OR 1.9; 95% CI 1.2,2.9), foetal macrosomia (OR 1.8; 95% CI 1.6,2.0), caesarean section (OR 1.9; 95% CI 1.8,2.0) and assisted conception (OR 1.9; 95% CI 1.6,2.1).
A specifically lower BMI references based on the potential public health action points for BMI classifications were a more sensitive predictor of adverse obstetric outcomes, and we recommend the use of these references in pregnancy especially among Asian population.
本研究旨在根据世界卫生组织(WHO)的体重指数(BMI)临界值,比较首次怀孕的超重孕妇与I级肥胖孕妇的产科结局,并确定WHO专家针对亚洲等高风险人群会诊所提出的潜在公共卫生行动要点。
这是一项回顾性队列研究,回顾了2010年至2012年从马来西亚国家妇产科登记处获得的数据。本研究纳入了所有首次怀孕且孕早期登记BMI的妇女。比较了WHO临界值定义的BMI分类与WHO专家会诊确定的针对不良产科结局的潜在公共卫生行动要点之间的关联。
本研究共纳入88,837名孕妇。我们注意到,即使在超重组中,使用WHO专家会诊确定的公共卫生行动要点时,不良产科结局的风险也显著更高,例如死产风险(比值比[OR]1.2;95%置信区间[CI]1.0,1.4)、肩难产(OR 1.9;95%CI 1.2,2.9)、巨大儿(OR 1.8;95%CI 1.6,2.0)、剖宫产(OR 1.9;95%CI 1.8,2.0)和辅助受孕(OR 1.9;95%CI 1.6,2.1)。
基于BMI分类的潜在公共卫生行动要点制定的特定较低BMI参考值,是不良产科结局更敏感的预测指标,我们建议在孕期尤其是亚洲人群中使用这些参考值。